Evidence map›Paper›PMID 34070351›Full record

ReviewJournal of clinical medicine2021

Sex Differences, Genetic and Environmental Influences on Dilated Cardiomyopathy.

Angita Jain, Nadine Norton, Katelyn A Bruno, Leslie T Cooper, Paldeep S Atwal, DeLisa Fairweather

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Sex Differences in Heart Failure: A Step Forward.Interventional cardiology (London, England) · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. The inflammatory spectrum of cardiomyopathies.Frontiers in cardiovascular medicine · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Identification ofDiagnostics (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Angita JainDepartment of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Nadine NortonDepartment of Cancer Biology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Katelyn A BrunoDepartment of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.ORCID 0000-0001-8980-6059
Leslie T CooperDepartment of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.ORCID 0000-0003-1002-3313
Paldeep S AtwalGenomic and Personalized Medicine, Atwal Clinic, 214 Brazilian Avenue, Suite 230, Palm Beach, FL 33480, USA.ORCID 0000-0002-8515-744X
DeLisa FairweatherDepartment of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Mayo Clinic in Florida · US

Funding

Role of viral mitophagosomes in driving sex differences in myocarditisR21AI145356 · NIAID · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA, SIN, JON · 2019 to 2020
$463k
Adipose-derived biogenic nanoparticles for treatment of myocarditis/DCM(MPDPI)R21AI152318 · NIAID · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA, WOLFRAM, JOY · 2020 to 2021
$430k
Vitamin D Binding Protein (DBP) in Innate Immune Cell Response in Viral MyocarditisR21AI163302 · NIAID · UNIVERSITY OF FLORIDA · PI BRUNO, KATELYN ANN · 2021 to 2022
$430k
Sex differences in exercise-induced mitochondrial function during viral myocarditisR21AI154927 · NIAID · MAYO CLINIC JACKSONVILLE · PI FAIRWEATHER, DELISA · 2020 to 2021
$403k
NIAID NIH HHS R21 AI145356NIAID NIH HHS R21 AI152318NIAID NIH HHS R21 AI154927NIAID NIH HHS R21 AI163302NIH HHS AI145356NIH HHS AI152318NIH HHS AI154927
6 · The paper itself

Abstract

Dilated cardiomyopathy (DCM) is characterized by dilatation of the left ventricle and impaired systolic function and is the second most common cause of heart failure after coronary heart disease. The etiology of DCM is diverse including genetic pathogenic variants, infection, inflammation, autoimmune diseases, exposure to chemicals/toxins as well as endocrine and neuromuscular causes. DCM is inherited in 20-50% of cases where more than 30 genes have been implicated in the development of DCM with pathogenic variants in

Indexed as

dilated cardiomyopathyenvironmentfamilial dilated cardiomyopathygenesidiopathic dilated cardiomyopathypathogenesissex differencessex ratiovirus

Identifiers

PMID34070351
PMCPMC8197492
OpenAlexW3164282092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.