Evidence map›Paper›PMID 34070317›Full record

ArticleInternational journal of molecular sciences2021

Attachment of Cancer Urothelial Cells to the Bladder Epithelium Occurs on Uroplakin-Negative Cells and Is Mediated by Desmosomal and Not by Classical Cadherins.

Urška Dragin Jerman, Tanja Višnjar, Iva Hafner Bratkovič, Nataša Resnik, Mojca Pavlin, Peter Veranič, Mateja Erdani Kreft

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Urška Dragin JermanInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Tanja VišnjarInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Iva Hafner BratkovičNational Institute of Chemistry, 1000 Ljubljana, Slovenia.ORCID 0000-0001-5635-931X
Nataša ResnikInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-3387-3487
Mojca PavlinGroup for Nano and Biotechnological Applications, Faculty of Electrical Engineering, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-5477-7833
Peter VeraničInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Mateja Erdani KreftInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6486-165X
University of Ljubljana · SIEN-FIST Centre of Excellence (Slovenia) · SI

Funding

Javna Agencija za Raziskovalno Dejavnost RS J7-2594Javna Agencija za Raziskovalno Dejavnost RS P3-0108Javna Agencija za Raziskovalno Dejavnost RS Z3-1872
6 · The paper itself

Abstract

Urinary bladder cancer is often multifocal; however, the intraluminal dissemination of the urothelial cancer cells is poorly understood. The involvement of N-cadherin in the adhesion of the cancer urothelial cells to the urothelium had not previously been studied. Therefore, we herein explore the possibility of the intraluminal dissemination of the urothelial cancer cells by evaluating the role of classical cadherins in the adhesion of urothelial cancer cells to the urothelium. We used E-cadherin negative T24 cells and established a T24 Ncad

Indexed as

Cell AdhesionCell Line, TumorCoculture TechniquesHumansNeoplasm ProteinsTight JunctionsUrinary BladderUrinary Bladder NeoplasmsUroplakinsUrotheliumNeoplasm ProteinsUroplakinsbladder cancerdesmosomeselectron microscopyN-cadherinurothelial in vitro models

Identifiers

PMID34070317
PMCPMC8197456
OpenAlexW3164526887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.