Evidence map›Paper›PMID 34070274›Full record

ArticleNutrients2021

Modulation of the Gut Microbiota Structure with Probiotics and Isoflavone Alleviates Metabolic Disorder in Ovariectomized Mice.

Qian Chen, Botao Wang, Shunhe Wang, Xin Qian, Xiu Li, Jianxin Zhao, Hao Zhang, Wei Chen, Gang Wang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Combination ofNutrients · 2026
    Article
  5. Review
  6. Oral Administration ofJournal of microbiology and biotechnology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Exploring the Potential ofInternational journal of medical sciences · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.Gastrointestinal disorders (Basel, Switzerland) · 2024
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qian ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Botao WangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.ORCID 0000-0002-0284-4560
Shunhe WangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Xin QianState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.ORCID 0000-0003-3330-7618
Xiu LiState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Jianxin ZhaoState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Hao ZhangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Wei ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Gang WangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.ORCID 0000-0003-2007-2143
Jiangnan University · CN

Funding

the Fundamental Research Funds for the Central Universities JUSRP22006, JUSRP51501the national first-class discipline program of Food Science and Technology JUFSTR20180102the National Natural Science Foundation of China No. 31972052, 32021005, 31820103010the Program of Collaborative Innovation Centre of Food Safety and Quality Control in Jiangsu Province none
6 · The paper itself

Abstract

The decrease in ovarian hormone secretion that occurs during menopause results in an increase in body weight and adipose tissue mass. Probiotics and soy isoflavones (SIFs) could affect the gut microbiota and exert anti-obesity effects. The objective of this study was to investigate the effects of probiotics and a diet containing SIF (SIF diet) on ovariectomized mice with menopausal obesity, including the gut microbiome. The results demonstrate that

Indexed as

AnimalsBifidobacterium longumFatty Acids, VolatileFecesFemaleGastrointestinal MicrobiomeHumansIsoflavonesLactiplantibacillus plantarumLipid MetabolismMenopauseMetabolic DiseasesMiceMice, Inbred C57BLObesityOvariectomyFatty Acids, VolatileIsoflavonesestrogenisoflavonesmenopausemicrobiotaobesityprobioticsshort-chain fatty acids

Identifiers

PMID34070274
PMCPMC8225012
OpenAlexW3165214014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.