Evidence map›Paper›PMID 34070267›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat.

Agnieszka Swiderska, Andrew M Coney, Abdulaziz A Alzahrani, Hayyaf S Aldossary, Nikolaos Batis, Clare J Ray, Prem Kumar, Andrew P Holmes

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Mechanisms of High-Altitude Acclimatization.International journal of molecular sciences · 2023
    Review
  4. Naphthoquinones Oxidize HInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Oxygen Sensing: Physiology and Pathophysiology.Antioxidants (Basel, Switzerland) · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Agnieszka SwiderskaInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0001-6968-965X
Andrew M ConeyInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0001-9451-4704
Abdulaziz A AlzahraniInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0001-5973-2802
Hayyaf S AldossaryInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0001-5449-8025
Nikolaos BatisInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0002-2305-7427
Clare J RayInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Prem KumarInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Andrew P HolmesInstitute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0001-9270-9401
University of Birmingham · GBKing Saud bin Abdulaziz University for Health Sciences · SAManchester Academic Health Science Centre · GBUmm al-Qura University · SA

Funding

King Saud bin Abdulaziz University for Health Sciences (Riyadh, Saudi Arabia) PhD ScholarshipUmm Al-Qura University (Makkah, Saudi Arabia) PhD ScholarshipWellcome Trust Institutional Strategic Support Fund Award
6 · The paper itself

Abstract

Reflex increases in breathing in response to acute hypoxia are dependent on activation of the carotid body (CB)-A specialised peripheral chemoreceptor. Central to CB O

Indexed as

carotid bodyhypoxiahypoxic ventilatory responsemitochondrial reactive oxygen speciessuccinatesuccinate dehydrogenase

Identifiers

PMID34070267
PMCPMC8225218
OpenAlexW3164576722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.