Evidence map›Paper›PMID 34070229›Full record

ArticlePolymers2021

On the Effectiveness of Oxygen Plasma and Alkali Surface Treatments to Modify the Properties of Polylactic Acid Scaffolds.

Ricardo Donate, María Elena Alemán-Domínguez, Mario Monzón

Abstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ricardo DonateGrupo de Investigación en Fabricación Integrada y Avanzada, Departamento de Ingeniería Mecánica, Universidad de Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas, Spain.ORCID 0000-0002-4337-5991
María Elena Alemán-DomínguezGrupo de Investigación en Fabricación Integrada y Avanzada, Departamento de Ingeniería Mecánica, Universidad de Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas, Spain.ORCID 0000-0002-2254-9905
Mario MonzónGrupo de Investigación en Fabricación Integrada y Avanzada, Departamento de Ingeniería Mecánica, Universidad de Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017 Las Palmas, Spain.ORCID 0000-0003-2736-7905

Funding

Canarian Agency for Research, Innovation and Information Society of the Canary Islands Regional Council for Employment, Industry, Commerce and Knowledge and by the European Social Fund (ESF) Canary Islands Integrated Operational Program 2014-2020 TESIS2017010036Science, Innovation and Universities Spanish Ministry BioAM project (DPI2017-88465-R)Spanish Ministry of Science and Innovation and ERDF funds UNLP10-3E-726 infrastructure project
6 · The paper itself

Abstract

Surface modification of 3D-printed PLA structures is a major issue in terms of increasing the biofunctionality and expanding the tissue engineering applications of these parts. In this paper, different exposure times were used for low-pressure oxygen plasma applied to PLA 3D-printed scaffolds. Alkali surface treatments were also evaluated, aiming to compare the modifications introduced on the surface properties by each strategy. Surface-treated samples were characterized through the quantification of carboxyl groups, energy-dispersive X-ray spectroscopy, water contact angle measurements, and differential scanning calorimetry analysis. The change in the surface properties was studied over a two-week period. In addition, an enzymatic degradation analysis was carried out to evaluate the effect of the surface treatments on the degradation profile of the 3D structures. The physicochemical characterization results suggest different mechanism pathways for each type of treatment. Alkali-treated scaffolds showed a higher concentration of carboxyl groups on their surface, which enhanced the enzymatic degradation rate, but were also proven to be more aggressive towards 3D-printed structures. In contrast, the application of the plasma treatments led to an increased hydrophilicity of the PLA surface without affecting the bulk properties. However, the changes on the properties were less steady over time.

Indexed as

additive manufacturingbiomedical applicationsenzymatic degradationlow-pressure plasmaplasma treatmentpolymersurface modificationtoluidine blue method

Identifiers

PMID34070229
PMCPMC8158707

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.