Evidence map›Paper›PMID 34070222›Full record

ArticleJournal of personalized medicine2021

Polygenic Panels Predicting the Susceptibility of Multiple Upper Aerodigestive Tract Cancer in Oral Cancer Patients.

Huei-Tzu Chien, Chi-Chin Yeh, Chi-Kuang Young, Tzu-Ping Chen, Chun-Ta Liao, Hung-Ming Wang, Kai-Lun Cho, Shiang-Fu Huang

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Huei-Tzu ChienDepartment of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Tao-Yuan 33302, Taiwan.ORCID 0000-0002-4120-7070
Chi-Chin YehMaster Program in Applied Molecular Epidemiology, College of Public Health, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-6483-1100
Chi-Kuang YoungDepartment of Otolaryngology, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.
Tzu-Ping ChenDepartment of Thoracic Surgery, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.
Chun-Ta LiaoDepartment of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou 33342, Taiwan.
Hung-Ming WangMedical College, Chang Gung University, Tao-Yuan 33302, Taiwan.
Kai-Lun ChoDepartment of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou 33342, Taiwan.
Shiang-Fu HuangDepartment of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou 33342, Taiwan.ORCID 0000-0003-3582-9938
Chang Gung University · TWChang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TWChina Medical University · TWKeelung Chang Gung Memorial Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPG3H0793, CMRPG3J0592 and CMRPB53Ministry of Health and Welfare MOHW109-TDU-B-212-134016Ministry of Science and Technology, Taiwan MOST 109-2314-B-182-015
6 · The paper itself

Abstract

Head and neck cancer was closely related with habitual use of cigarette and alcohol. Those cancer patients are susceptible to develop multiple primary tumors (MPTs). In this study, we utilized the single nucleotide polymorphisms (SNPs) array (Affymetrix Axion Genome-Wide TWB 2.0 Array Plate) to investigate patients' risks of developing multiple primary cancers. We recruited 712 male head and neck cancer patients between Mar 1996 and Feb 2017. Two hundred and eighty-six patients (40.2%) had MPTs and 426 (59.8%) had single cancer. Four hundred and twelve normal controls were also recruited. A list of seventeen factors was extracted and ten factors were demonstrated to increase the risks of multiple primary cancers (alcohol drinking, rs118169127, rs149089400, rs76367287, rs61401220, rs141057871, rs7129229, older age, rs3760265, rs9554264; all were

Indexed as

head and neck cancermultiple primary cancersingle nucleotide polymorphismSNP arrayupper aerodigestive tract

Identifiers

PMID34070222
PMCPMC8158753
OpenAlexW3160879094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.