Evidence map›Paper›PMID 34070219›Full record

ArticleInternational journal of molecular sciences2021

Constitutive Expression of TERT Enhances β-Klotho Expression and Improves Age-Related Deterioration in Early Bovine Embryos.

Lianguang Xu, Muhammad Idrees, Myeong-Don Joo, Tabinda Sidrat, Yiran Wei, Seok-Hwan Song, Kyeong-Lim Lee, Il-Keun Kong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. The Possible Roles ofCurrent medicinal chemistry · 2025
    Review
  4. Article
  5. Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserveThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lianguang XuDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.
Muhammad IdreesDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.ORCID 0000-0002-9715-0691
Myeong-Don JooDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.
Tabinda SidratDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.
Yiran WeiDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.
Seok-Hwan SongThe Kingkong Co., Ltd., Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.
Kyeong-Lim LeeThe Kingkong Co., Ltd., Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.ORCID 0000-0001-6707-2736
Il-Keun KongDivision of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju 52828, Gyeongnam Province, Korea.ORCID 0000-0001-5567-1088
Gyeongsang National University · KR

Funding

Ministry of Agriculture, Food and Rural Affairs 120066-01National Research Foundation of Korea 2020R1A2C2006614
6 · The paper itself

Abstract

Age-associated decline in oocyte quality is one of the dominant factors of low fertility. Aging alters several key processes, such as telomere lengthening, cell senescence, and cellular longevity of granulosa cells surrounding oocyte. To investigate the age-dependent molecular changes, we examined the expression, localization, and correlation of telomerase reverse transcriptase (

Indexed as

AgingAnimalsBlastocystCattleCells, CulturedCleavage Stage, OvumEmbryo ImplantationEmbryonic DevelopmentFemaleGene ExpressionGranulosa CellsMembrane ProteinsOocytesPregnancyPregnancy, AnimalReactive Oxygen SpeciesMembrane ProteinsReactive Oxygen SpeciesReceptor, Fibroblast Growth Factor, Type 1Telomerasebovine embryocycloastragenolFGFR1TERTβ-Klotho

Identifiers

PMID34070219
PMCPMC8158768
OpenAlexW3160371557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.