Evidence map›Paper›PMID 34070099›Full record

ArticleMolecules (Basel, Switzerland)2021

Neuroprotective Effect and Antioxidant Potency of Fermented Cultured Wild Ginseng Root Extracts of

Chul-Joong Kim, Hyeon-Yeol Ryu, Somin Lee, Han-Joo Lee, Yoon-Soek Chun, Jong-Kyu Kim, Chang-Yeon Yu, Bimal Kumar Ghimire, Jae-Geun Lee

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  9. Beneficial Effects ofMicroorganisms · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chul-Joong KimResearch Institute of Biotechnology, HwajinBioCosmetics CO., LTD, Chuncheon 24232, Korea.ORCID 0000-0002-8071-9327
Hyeon-Yeol RyuKorea Conformity Laboratories, Yeonsu, Incheon 21999, Korea.ORCID 0000-0002-8490-006X
Somin LeeKorea Conformity Laboratories, Yeonsu, Incheon 21999, Korea.ORCID 0000-0002-4899-0336
Han-Joo LeeAribio H&B CO.LTD, Yongin 16914, Korea.ORCID 0000-0002-6453-3557
Yoon-Soek ChunAribio H&B CO.LTD, Yongin 16914, Korea.ORCID 0000-0002-2802-2442
Jong-Kyu KimAribio H&B CO.LTD, Yongin 16914, Korea.ORCID 0000-0002-1775-8438
Chang-Yeon YuDepartment of Bio-Resource Sciences, Kangwon National University, Chuncheon 21341, Korea.
Bimal Kumar GhimireDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Gwangjin, Seoul 05029, Korea.
Jae-Geun LeeResearch Institute of Biotechnology, HwajinBioCosmetics CO., LTD, Chuncheon 24232, Korea.ORCID 0000-0002-8352-8059
Korea Testing Laboratory · KRKangwon National University · KRKonkuk University · KR

Funding

This research was funded by the Ministry of SMEs and Startups (the project of Support for Joint Utilization of Research Facilities and Equipment). NT19-00122
6 · The paper itself

Abstract

Wild ginseng has better pharmacological effects than cultivated ginseng. However, its industrialization is limited by the inability to grow wild ginseng on a large scale. Herein, we demonstrate how to optimize ginseng production through cultivation, and how to enhance the concentrations of specific ginsenosides through fermentation. In the study, we also evaluated the ability of fermented cultured wild ginseng root extract (HLJG0701-β) to inhibit acetylcholinesterase (AChE), as well as its neuroprotective effects and antioxidant activity. In

Indexed as

FermentationAcetylcholineAcetylcholinesteraseAnimalsAntioxidantsBrainCatalaseCholinesterase InhibitorsDisease Models, AnimalFemaleGalactoseGinsenosidesMaleMalondialdehydeMiceMorris Water Maze TestAcetylcholineAcetylcholinesteraseAntioxidantsCatalaseCholinesterase InhibitorsGalactoseGinsenosidesMalondialdehydeNeuroprotective AgentsPlant ExtractsReactive Oxygen SpeciesScopolamineacetylcholinesteraseantioxidantcultured wild ginseng rootsginsenosidesmemory deficitPediococcus pentosaceus

Identifiers

PMID34070099
PMCPMC8158381
OpenAlexW3165726635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.