Evidence map›Paper›PMID 34070034›Full record

ArticleJournal of clinical medicine2021

Prognosis of Coronary Atherosclerotic Burden in Non-Ischemic Dilated Cardiomyopathies.

Marjorie Canu, Léa Margerit, Ismail Mekhdoul, Alexis Broisat, Laurent Riou, Loïc Djaileb, Clémence Charlon, Adrien Jankowski, Michele Magnesa, Caroline Augier and 9 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Characteristics of the phenotype of mixed cardiomyopathy in patients with implantable cardioverter-defibrillators.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marjorie CanuDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Léa MargeritDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Ismail MekhdoulDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Alexis BroisatINSERM, U1039, Radiopharmaceutiques Biocliniques, Grenoble Alpes University, 38000 Grenoble Alpes, France.ORCID 0000-0002-4265-8463
Laurent RiouINSERM, U1039, Radiopharmaceutiques Biocliniques, Grenoble Alpes University, 38000 Grenoble Alpes, France.
Loïc DjailebINSERM, U1039, Radiopharmaceutiques Biocliniques, Grenoble Alpes University, 38000 Grenoble Alpes, France.
Clémence CharlonDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Adrien JankowskiDepartment of Radiology, University Hospital, 38000 Grenoble Alpes, France.
Michele MagnesaDepartment of Medical & Surgical Sciences, University of Foggia, 71121 Foggia, Italy.
Caroline AugierDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Stéphanie MarlièreDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Muriel SalvatDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Charlotte CassetDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Marion MaurinDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.ORCID 0000-0003-4156-3208
Carole SaunierDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Daniel FagretINSERM, U1039, Radiopharmaceutiques Biocliniques, Grenoble Alpes University, 38000 Grenoble Alpes, France.
Catherine GhezziINSERM, U1039, Radiopharmaceutiques Biocliniques, Grenoble Alpes University, 38000 Grenoble Alpes, France.
Gerald VanzettoDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.
Gilles Barone-RochetteDepartment of Cardiology, University Hospital, 38000 Grenoble Alpes, France.ORCID 0000-0002-1146-0542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherosclerosis is associated with a worse prognosis in many diseases such as ischemic cardiomyopathy, but its impact in non-ischemic dilated cardiomyopathy (dCMP) is lesser known. Our aim was to study the prognostic impact of coronary atherosclerotic burden (CAB) in patients with dCMP.

methodsConsecutive patients with dCMP and left ventricular (LV) dysfunction diagnosed by concomitant analysis of invasive coronary angiography (ICA) and CMR imaging were identified from registry-database. CAB was measured by Gensini score. The primary composite endpoint was the occurrence of major adverse cardiovascular events (MACE) defined as cardiovascular (CV) mortality, non-fatal MI and unplanned myocardial revascularization. The results of 139 patients constituting the prospective study population (mean age 59.4 ± 14.7 years old, 74% male), average LV ejection fraction was 31.1 ± 11.02%, median Gensini score was 0 (0-3), and mid-wall late gadolinium enhancement (LGE) was the most frequent LGE pattern (42%). Over a median follow-up of 2.8 years, 9% of patients presented MACE. Patients with MACE had significantly higher CAB compared to those who were free of events (0 (0-3) vs. 3.75 (2-15),

conclusionHigh CAB may be a new prognostic factor in dCMP patients.

Indexed as

cardiac magnetic resonance imagingcoronary atherosclerotic burdendilated cardiomyopathy

Identifiers

PMID34070034
PMCPMC8158137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.