Evidence map›Paper›PMID 34070005›Full record

ArticleInternational journal of environmental research and public health2021

Clinical Relevance of Urine Flow Rate and Exposure to Polycyclic Aromatic Hydrocarbons.

Po-Hsuan Jeng, Tien-Ru Huang, Chung-Ching Wang, Wei-Liang Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Po-Hsuan JengDepartment of General Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-5821-0460
Tien-Ru HuangDepartment of General Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Chung-Ching WangDepartment of Family and Community Medicine, Division of Family Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0003-2808-4763
Wei-Liang ChenDepartment of Family and Community Medicine, Division of Family Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0003-0784-230X
Tri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycyclic aromatic hydrocarbon (PAH) metabolites have received increasing attention because several of these organic substances are highly carcinogenic or mutagenic. Exposure to PAHs is associated with many harmful health effects; however, we are not aware of any study that has explored the exposure to PAHs and urinary conditions in the general population. The present work aimed to investigate the correlation among PAH and urine flow rate (UFR).

methodCross-sectional data from the National Health and Nutrition Examination Survey (NHANES) 2009-2012 were used in our study. A total of 4172 participants and a total of nine PAH metabolites were examined. The UFR was measured as the amount of urine excreted in a period of time (mL/h). Several covariates were adjusted in linear regression models.

resultAfter adjusting for variables, the PAH metabolites in urine showed a significant correlation with UFR. Dose-dependent associations between PAH metabolites in the urine and UFR were also found. Higher quartiles of PAH metabolites in urine exhibited higher regression coefficients.

conclusionOur study highlighted that PAH metabolites in urine had a strong association with decreased UFR in the US adult population. These findings support the possibility that PAH exposure is related to bladder dysfunction. Further prospective studies are warranted.

Indexed as

Polycyclic Aromatic HydrocarbonsAdultBiomarkersCarcinogensCross-Sectional StudiesHumansNutrition SurveysProspective StudiesBiomarkersCarcinogensPolycyclic Aromatic Hydrocarbonsbladder dysfunctioncross-sectional dataNational Health and Nutrition Examination Surveypolycyclic aromatic hydrocarbonsurine flow rate

Identifiers

PMID34070005
PMCPMC8157826
OpenAlexW3162536196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.