Evidence map›Paper›PMID 34070002›Full record

ArticleBrain sciences2021

Changes in the Brain Activity and Visual Performance of Patients with Strabismus and Amblyopia after a Compete Cycle of Light Therapy.

Danjela Ibrahimi, Jorge D Mendiola-Santibañez, Enoé Cruz-Martínez, Alfonso Gómez-Espinosa, Irineo Torres-Pacheco

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danjela IbrahimiFacultad de Medicina, Universidad Autónoma de Querétaro, Santiago de Querétaro 76176, Mexico.ORCID 0000-0002-5103-082X
Jorge D Mendiola-SantibañezFacultad de Ingeniería, Universidad Autónoma de Querétaro, Santiago de Querétaro 76010, Mexico.ORCID 0000-0002-9173-0732
Enoé Cruz-MartínezHospital Infantil Teletón de Oncología, Anillo Vial Junipero Serra 1999, Santiago de Querétaro 76140, Mexico.
Alfonso Gómez-EspinosaEscuela de Ingenieria y Ciencias, Tecnologico de Monterrey, Av. Epigmenio González 500, Fracc. San Pablo, Santiago de Querétaro 76130, Mexico.ORCID 0000-0001-5657-380X
Irineo Torres-PachecoFacultad de Ingeniería, Universidad Autónoma de Querétaro, Santiago de Querétaro 76010, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research assesses the brain activity and visual performance at baseline and after light therapy (LTH), of seventeen patients with strabismus and amblyopia (SA), and eleven healthy controls (HCs) from Querétaro, México. Quantitative electroencephalogram analysis (qEEG) was used to record the brain activity, and clinical metrics such as the visual acuity, angle of deviation, phoria state, stereopsis, and visual fields determined the visual performance. Results showed a constant higher alpha-wave frequency for HCs. Low voltages remained negative for HCs and positive for SA patients across stimulation. After LTH, high voltage increased in SA patients, and decreased in HCs. A second spectral peak, (theta-wave), was exclusively recorded in SA patients, at baseline and after LTH. Positive Spearman correlations for alpha-wave frequency, low and high voltages were only seen in SA patients. Synchronized brain activity was recorded in all SA patients stimulated with filters transmitting light in the blue but not in the red spectrum. Enhancement in the visual performance of SA patients was found, whereas deterioration of the phoria state and a decrease in the amount of stereopsis was seen in HCs. To conclude, only a suffering brain and a visual pathway which needs to be enabled can benefit from LTH.

Indexed as

amblyopiabrain activitylight therapyquantitative electroencephalographystrabismus

Identifiers

PMID34070002
PMCPMC8157857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.