Evidence map›Paper›PMID 34069995›Full record

ArticleGenes2021

Alpha-Actinin-3 Deficiency Might Affect Recovery from Non-Contact Muscle Injuries: Preliminary Findings in a Top-Level Soccer Team.

Gil Rodas, Víctor Moreno-Pérez, Juan Del Coso, Daniel Florit, Lourdes Osaba, Alejandro Lucia

Abstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Role ofGenes · 2026
    Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. TheSports (Basel, Switzerland) · 2025
    Article
  7. TheGenes · 2025
    Article
  8. Review
  9. Testing in Football: A Narrative Review.Sports (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Genes · 2024
    Article
  12. Article
  13. Article
  14. Association of theGenes · 2022
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gil RodasMedical Department, Futbol Club Barcelona, Barça Innovation Hub, 08028 Barcelona, Spain.ORCID 0000-0002-8060-3914
Víctor Moreno-PérezCenter for Translational Research in Physiotherapy, Department of Pathology and Surgery, Miguel Hernandez University of Elche, 03202 Elche, Spain.
Juan Del CosoCentre for Sport Studies, Rey Juan Carlos University, 28943 Fuenlabrada, Spain.ORCID 0000-0002-5785-984X
Daniel FloritMedical Department, Futbol Club Barcelona, Barça Innovation Hub, 08028 Barcelona, Spain.
Lourdes OsabaProgenika Biopharma, A Grifols Company, 48160 Derio, Spain.
Alejandro LuciaFaculty of Sport Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are recent data suggesting an association between the R577X polymorphism (rs1815739) in the gene encoding α-actinin-3 (

Indexed as

ActininAdultAllelesAthletesFemaleGenotypeHumansMaleMusclesMuscular DiseasesPolymorphism, Single NucleotideRunningSoccerActininACTN3 protein, humanelite athletefootballgeneticmuscle strainsports injury

Identifiers

PMID34069995
PMCPMC8157848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.