Evidence map›Paper›PMID 34069970›Full record

ArticleInternational journal of molecular sciences2021

δ-Catenin Participates in EGF/AKT/p21

Yingjie Shen, Hyoung Jae Lee, Rui Zhou, Hangun Kim, Gen Chen, Young-Chang Cho, Kwonseop Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Targeting PI3K/Akt signaling in prostate cancer therapy.Journal of cell communication and signaling · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Delta-Catenin as a Modulator of Rho GTPases in Neurons.Frontiers in cellular neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yingjie ShenCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju 61186, Korea.
Hyoung Jae LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0002-4724-5908
Rui ZhouCollege of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Sunchon 57922, Korea.
Hangun KimCollege of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Sunchon 57922, Korea.
Gen ChenCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju 61186, Korea.
Young-Chang ChoCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju 61186, Korea.
Kwonseop KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0003-3560-6005
Chonnam National University · KRSunchon National University · KR

Funding

National Research Foundation of Korea NRF-2019R1I1A3A01061094
6 · The paper itself

Abstract

Prostate cancer (PCa) is the second most leading cause of death in males. Our previous studies have demonstrated that δ-catenin plays an important role in prostate cancer progression. However, the molecular mechanism underlying the regulation of δ-catenin has not been fully explored yet. In the present study, we found that δ-catenin could induce phosphorylation of p21

Indexed as

Active Transport, Cell NucleusBinding SitesCateninsCell Line, TumorCell ProliferationCyclin-Dependent Kinase Inhibitor p21Delta CateninEpidermal Growth FactorHumansLigandsMaleModels, BiologicalMutagenesis, Site-DirectedNeoplasm InvasivenessPC-3 CellsPhosphorylationCateninsCDKN1A protein, humanCyclin-Dependent Kinase Inhibitor p21Delta CateninEpidermal Growth FactorLigandsProto-Oncogene Proteins c-aktThreonineAKTEGFp21Wafprostate cancerδ-catenin

Identifiers

PMID34069970
PMCPMC8157876
OpenAlexW3163859206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.