Evidence map›Paper›PMID 34069906›Full record

ArticleNutrients2021

Comparative Gene Signature of (-)-Oleocanthal Formulation Treatments in Heterogeneous Triple Negative Breast Tumor Models: Oncological Therapeutic Target Insights.

Mohammed H Qusa, Khaldoun S Abdelwahed, Abu Bakar Siddique, Khalid A El Sayed

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The Olive PhenolicNutrients · 2025
    Article
  4. Review
  5. The Olive Oil PhenolicNutrients · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammed H QusaSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.
Khaldoun S AbdelwahedSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.
Abu Bakar SiddiqueSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.ORCID 0000-0001-5424-9475
Khalid A El SayedSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.ORCID 0000-0002-1456-4064

Funding

Oleocanthal functional food products for breast cancer recurrence controlR41CA247025 · NCI · OLEOLIVE, INC. · PI EL SAYED, KHALID A · 2020 to 2021
$455k
Louisiana Board of Regents LEQSF (2017-20)-RD-B-07NCI NIH HHS R41 CA247025NCI NIH HHS R41CA247025
6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) heterogeneity and limited therapeutic options confer its phenotypic aggressiveness. The discovery of anti-TNBC natural products with valid molecular target(s) and defined pharmacodynamic profile would facilitate their therapeutic nutraceutical use by TNBC patients. The extra-virgin olive oil (EVOO) is a key Mediterranean diet ingredient.

Indexed as

AldehydesAnimalsCell Line, TumorCyclopentane MonoterpenesDisease Models, AnimalFemaleGene Expression Regulation, NeoplasticHumansMiceOlive OilPhenolsTriple Negative Breast NeoplasmsAldehydesCyclopentane MonoterpenesoleocanthalOlive OilPhenolsextra-virgin olive oilmicroarrayMMTV-PyVT(−)-oleocanthalPDXTNBC

Identifiers

PMID34069906
PMCPMC8157589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.