Evidence map›Paper›PMID 34069814›Full record

ArticleInternational journal of molecular sciences2021

Calvaria Bone Transcriptome in Mouse Models of Osteogenesis Imperfecta.

Pierre Moffatt, Iris Boraschi-Diaz, Juliana Marulanda, Ghalib Bardai, Frank Rauch

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. New lens on congenital mild bone fragility: a novel Col1a1 knockout mouse model for osteogenesis imperfecta type 1.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  3. Identification of common genetic features and pathways for osteoporosis with frozen shoulder by integrated bioinformatics analysis and machine learning.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  4. Article
  5. Article
  6. Targeting Longevity GeneMetabolites · 2023
    Article
  7. Review
  8. Article
  9. Exploration of the skeletal phenotype of theFrontiers in endocrinology · 2023
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pierre MoffattShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.ORCID 0000-0002-5793-1944
Iris Boraschi-DiazShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Juliana MarulandaShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Ghalib BardaiShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Frank RauchShriners Hospital for Children-Canada, Montreal, QC H4A 0A9, Canada.
Shriners Hospitals for Children - Canada · CA

Funding

Consortium québécois sur la découverte du médicament A456-09Réseau de recherche en santé buccodentaire et osseuse 67070
6 · The paper itself

Abstract

Osteogenesis imperfecta (OI) is a bone fragility disorder that is usually caused by mutations affecting collagen type I. We compared the calvaria bone tissue transcriptome of male 10-week-old heterozygous Jrt (

Indexed as

AnimalsCollagen Type IDicarboxylic Acid TransportersDisease Models, AnimalFemurGene Expression ProfilingHeterozygoteHomozygoteMaleMiceMutationOsteogenesisOsteogenesis ImperfectaSkullSphingomyelin PhosphodiesteraseSymportersCollagen Type IDicarboxylic Acid TransportersSlc13a5 protein, mouseSmpd3 protein, mouseSphingomyelin PhosphodiesteraseSymportersosteogenesis imperfectaRNA sequencingtransforming growth factor betaWnt signaling

Identifiers

PMID34069814
PMCPMC8157281
OpenAlexW3162250795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.