ArticleBrain sciences2021
Is the Age of Developmental Milestones a Predictor for Future Development in Down Syndrome?
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Novel CTNNB1 Gene Variants in Spanish CTNNB1 Syndrome Patients: Clinical and Psychological Manifestations.Journal of autism and developmental disorders · 2026Article
- Developmental Profile and Variability in Preschool-Age Children With Down Syndrome.Journal of intellectual disability research : JIDR · 2026Article
- Review of early development in children with Down syndrome: family and clinician partnership.BMJ paediatrics open · 2026Review
- Age of early milestones achievement and developmental outcome in children with Down syndrome.International journal of developmental disabilities · 2026Article
- Babble Boot Camp for Infants With Down Syndrome: Piloting a Proactive, Caregiver-Led Intervention Designed to Boost Earliest Speech and Language Skills.American journal of speech-language pathology · 2025Article
- Concurrent validity in language and motor domains on the Vineland-3 and Mullen Scales of Early Learning in young children with Down syndrome.Research in developmental disabilities · 2025Article
- Parental knowledge of developmental milestones in Peshawar, Pakistan: a cross-sectional study.European journal of pediatrics · 2025Article
- Article
- Impaired neutrophil-mediated cell death drives Ewing's Sarcoma in the background of Down syndrome.Frontiers in oncology · 2024Article
- Vocal Characteristics of Infants at Risk for Speech Motor Involvement: A Scoping Review.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Article
- Individual and cumulative risk factors in developmental language disorder: A case-control study.Clinical child psychology and psychiatry · 2023Article
- Motor-language links in children with Down syndrome: a scoping review to revisit the literature with a developmental cascades lens.Frontiers in psychology · 2023Article
- Impact of Neonatal Body (Dis)Proportionality Determined by the Cephalization Index (CI) on Gross Motor Development in Children with Down Syndrome: A Prospective Cohort Study.Children (Basel, Switzerland) · 2022Article
- Individuals with Down Syndrome: Editorial.Brain sciences · 2022Article
- A reassessment of Jackson's checklist and identification of two Down syndrome sub-phenotypes.Scientific reports · 2022Article
- Cognitive profiles in children and adolescents with Down syndrome.Scientific reports · 2022Article
- Early predictors of language outcomes in Down syndrome: A mini-review.Frontiers in psychology · 2022Review
- Development of Down Syndrome Research Over the Last Decades-What Healthcare and Education Professionals Need to Know.Frontiers in psychiatry · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Down Syndrome (DS) is the most common genetic alteration responsible for intellectual disability, which refers to deficits in both intellectual and adaptive functioning. According to this, individuals with Down Syndrome (DS) reach developmental milestones (e.g., sitting, walking, and babbling) in the same order as their typically developing peers, but later in life. Since developmental milestones are the first blocks on which development builds, the aims of the current study are to: (i) expand the knowledge of developmental milestone acquisition; and (ii) explore the relationship between developmental milestone acquisition and later development. For this purpose 105 children/adolescents with DS were involved in this study, divided in two groups, Preschoolers (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.