ArticleJournal of clinical medicine2021
Analysis of Frailty in Geriatric Patients as a Prognostic Factor in Endovascular Treated Patients with Large Vessel Occlusion Strokes.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Treatment-modifying effects of frailty on stroke reperfusion therapy outcomes: a systematic review and meta-analysis.Age and ageing · 2026Pooled it
- Role of frailty in predicting outcomes after stroke: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease.Current cardiology reviews · 2024Pooled it
- Implications of frailty in acute ischemic stroke receiving endovascular treatment: systematic review and meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Prevalence and Risk Factors of Frailty in Stroke Patients: A Meta-Analysis and Systematic Review.The journal of nutrition, health & aging · 2023Pooled it
- Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis.Age and ageing · 2022Pooled it
- Review
- The predictive value of the hospital frailty risk score for 28-day mortality in older critically ill patients with acute ischemic stroke.BMC geriatrics · 2026Article
- Narrative Review on Post-Stroke Outcomes Through Recognition of Frailty, Sarcopenia, and Palliative Care Needs.Healthcare (Basel, Switzerland) · 2025Review
- Frailty and stroke: Global implications for assessment, research, and clinical care-A WSO scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025Review
- Frailty in Stroke Care in Germany Between 2016 and 2022-A Retrospective, Hospital-Based Nationwide Cohort Study.NeuroSci · 2025Article
- Prevalence of frailty among older patients with acute ischemic stroke and its association with short-term functional outcome: a cohort study in Vietnam.BMC geriatrics · 2025Article
- Association between Pre-stroke Frailty and Clinical Outcomes: A Systematic Review and Meta-analysis.Physical therapy research · 2025Review
- Development and validation of a biological frailty score based on CRP, haemoglobin, albumin and vitamin D within an electronic health record database in France: a cross-sectional study.BMJ public health · 2025Article
- Association Between Premorbid Frailty Status and Functional Independence in Acute Ischemic Stroke Patients Following Endovascular Treatment in the Late Window.Clinical interventions in aging · 2025Article
- Impact of Frailty Risk on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage: A Historical Cohort Study.Neurologia medico-chirurgica · 2024Article
- Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations.Biomedicines · 2023Review
- Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses.Stroke · 2023Observational
- Advance of Thrombolysis and Thrombectomy in Acute Ischemic Stroke.Journal of clinical medicine · 2023Article
- [Cardiovascular risk factors, haemostasis and antithrombotic treatment in retinal vessel occlusion].Die Ophthalmologie · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is associated with an increased risk of adverse health-care outcomes in elderly patients. The Hospital Frailty Risk Score (HFRS) has been developed and proven to be capable of identifying patients which are at high risk of adverse outcomes. We aimed to investigate whether frail patients also face adverse outcomes after experiencing an endovascular treated large vessel occlusion stroke (LVOS). In this retrospective observational cohort study, we analyzed patients ≥ 65 years that were admitted during 2015-2019 with LVOS and endovascular treatment. Primary outcomes were mortality and the modified Rankin Scale (mRS) after three months. Regression models were used to determine the impact of frailty. A total of 318 patients were included in the cohort. The median HFRS was 1.6 (IQR 4.8). A total of 238 (75.1%) patients fulfilled the criteria for a low-frailty risk with a HFRS < 5.72 (22.7%) for moderate-frailty risk with an HFRS from 5-15 and 7 (2.2%) patients for a high-frailty risk. Multivariate regression analyses revealed that the HFRS was associated with an increased mortality after 90 days (CI (95%) 1.001 to 1.236; OR 1.112) and a worse mRS (CI (95%) 1.004 to 1.270; OR 1.129). We identified frailty as an impact factor on functional outcome and mortality in patients undergoing thrombectomy in LVOS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.