Evidence map›Paper›PMID 34069753›Full record

ArticleInternational journal of molecular sciences2021

X-ray Crystallographic Structure of α-Helical Peptide Stabilized by Hydrocarbon Stapling at

Yui Makura, Atsushi Ueda, Takuma Kato, Akihiro Iyoshi, Mei Higuchi, Mitsunobu Doi, Masakazu Tanaka

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yui MakuraGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Atsushi UedaGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Takuma KatoFaculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan.
Akihiro IyoshiGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Mei HiguchiGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Mitsunobu DoiFaculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan.
Masakazu TanakaGraduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.

Funding

Japan Society for the Promotion of Science JP17H03998Japan Society for the Promotion of Science JP18K14870Japan Society for the Promotion of Science JP20K06967Shionogi Award in Synthetic Organic Chemistry, Japan n/aUbe Industries n/a
6 · The paper itself

Abstract

Hydrocarbon stapling is a useful tool for stabilizing the secondary structure of peptides. Among several methods, hydrocarbon stapling at

Indexed as

AlkenesAmino AcidsAmino Acid SequenceCircular DichroismCrystallography, X-RayHydrocarbonsOligopeptidesPeptidesProlineProtein Conformation, alpha-HelicalProtein StabilityProtein Structure, SecondaryX-RaysAlkenesAmino AcidsHydrocarbonsOligopeptidesPeptidesProlinehydrocarbon staplingi,i + 1 staplepeptidering-closing metathesisX-ray structureα-helix

Identifiers

PMID34069753
PMCPMC8160927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.