Evidence map›Paper›PMID 34069719›Full record

ArticleAnimals : an open access journal from MDPI2021

Characterization of Microbiome on Feces, Blood and Milk in Dairy Cows with Different Milk Leucocyte Pattern.

Elisa Scarsella, Alfonso Zecconi, Michela Cintio, Bruno Stefanon

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

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  14. Colonization and development of the gut microbiome in calves.Journal of animal science and biotechnology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elisa ScarsellaDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-1463-4608
Alfonso ZecconiDepartment of Biomedical, Surgical and Dental Sciences-One Health Unit, University of Milan, 20100 Milan, Italy.ORCID 0000-0002-3127-8385
Michela CintioDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-3078-6177
Bruno StefanonDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-7414-5830
University of Udine · ITUniversity of Milan · IT

Funding

Ministero delle Politiche Agricole Alimentari e Forestali D.M. 16815/7100/2019, BESTMILK project.
6 · The paper itself

Abstract

Mastitis is an inflammatory disease of the mammary gland, caused by the invasion of microorganism on this site, associated with an altered immune response. Recent studies in this field hypothesize that the origin of these pathogens can also be from the gastrointestinal tract, through the entero-mammary pathway in relation to an increase in gut permeability. In this study, we wanted to investigate if inflammatory status of the mammary gland is related to an alteration of gut permeability. The microbiome of feces, blood and milk of lactating cows, recruited on the basis of the total somatic cell count and of the percentage of polymorphonuclear neutrophils and lymphocytes, was studied. Cows were divided into healthy (G), at risk of mastitis (Y) and with mastitis (R) classifications. The bacterial DNA was extracted and the V3 and V4 regions of 16S rRNA sequenced. Moreover, the quantification of total bacteria was performed with quantitative real-time PCR. A non-parametric Kruskal-Wallis test was applied at the phylum, family and genera levels and beta biodiversity was evaluated with the unweighted UniFrac distance metric. Significant differences between groups were found for the microbial composition of feces (Clostridiaceae, Turicibacteriaceae for family level and

Indexed as

bovineentero-mammary pathwaymastitismicrobiome

Identifiers

PMID34069719
PMCPMC8160755
OpenAlexW3161793298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.