Evidence map›Paper›PMID 34069696›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Haplopine Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice and TNF-α/IFN-γ-Induced Inflammation in Human Keratinocyte.

Tae-Young Kim, Ye Jin Kim, Jonghwan Jegal, Beom-Geun Jo, Han-Seok Choi, Min Hye Yang

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Nutrients · 2024
    Article
  6. Can agedFrontiers in pharmacology · 2024
    Article
  7. Article
  8. Article
  9. Keratinocyte Response to Infection withJournal of fungi (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Oxidative Stress and Gut Microbiome in Inflammatory Skin Diseases.Frontiers in cell and developmental biology · 2022
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tae-Young KimCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Ye Jin KimC&D Research Team, R&D Strategy Center, Genuonesciences, Seoul 06800, Korea.
Jonghwan JegalCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Beom-Geun JoCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Han-Seok ChoiC&D Research Team, R&D Strategy Center, Genuonesciences, Seoul 06800, Korea.
Min Hye YangCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Pusan National University · KR

Funding

National Research Foundation of Korea NRF-2019M3A9I3080266 and 2019M3A9I3080267
6 · The paper itself

Abstract

This study aimed to investigate the anti-inflammatory, antioxidant, and anti-atopic dermatitis (AD) effects of haplopine, which is one of the active components in

Indexed as

2,4-dinitrochlorobenzeneatopic dermatitisBalb/c miceHaCaT cellshaplopineJurkat T cells

Identifiers

PMID34069696
PMCPMC8161082
OpenAlexW3161884494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.