Evidence map›Paper›PMID 34069630›Full record

Observational studyNutrients2021

Dietary Patterns of Breastfeeding Mothers and Human Milk Composition: Data from the Italian MEDIDIET Study.

Francesca Bravi, Matteo Di Maso, Simone R B M Eussen, Carlo Agostoni, Guglielmo Salvatori, Claudio Profeti, Paola Tonetto, Pasqua Anna Quitadamo, Iwona Kazmierska, Elisabetta Vacca and 6 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  8. Observational
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  16. Review
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  18. Importance of human milk for infants in the clinical setting: Updates and mechanistic links.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Francesca BraviDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-0173-5319
Matteo Di MasoDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.
Simone R B M EussenDanone Nutricia Research, 3584 Utrecht, The Netherlands.ORCID 0000-0001-5621-7944
Carlo AgostoniPediatric Intermediate Care Unit, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-5006-0832
Guglielmo SalvatoriNeonatal Intensive Care Unit, IRCCS Ospedale Pediatrico Bambino Gesù, 00165 Rome, Italy.
Claudio ProfetiNeonatal Intensive Care Unit, Azienda Ospedaliera Universitaria Meyer di Firenze, 50139 Florence, Italy.
Paola TonettoNeonatal Care Unit of the University, City of Health and Science Hospital, 10126 Turin, Italy.
Pasqua Anna QuitadamoNeonatology-Neonatal Intensive Care Unit, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.
Iwona KazmierskaNeonatal Intensive Care Unit, Ospedale Buccheri La Ferla Fatebenefratelli, 90123 Palermo, Italy.
Elisabetta VaccaDanone Nutricia Research, 3584 Utrecht, The Netherlands.
Adriano DecarliDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-1451-8292
Bernd StahlDanone Nutricia Research, 3584 Utrecht, The Netherlands.
Enrico BertinoNeonatal Care Unit of the University, City of Health and Science Hospital, 10126 Turin, Italy.
Guido E MoroItalian Association of Human Milk Banks (AIBLUD), 20126 Milan, Italy.ORCID 0000-0002-3429-3257
Monica FerraroniDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-4542-4996
On Behalf Of The Medidiet Working Group
University of Milan · ITDanone (Netherlands) · NLBambino Gesù Children's Hospital · ITCasa Sollievo della Sofferenza · ITMeyer Children's Hospital · ITOspedale Buccheri la Ferla Fatebenefratelli · ITUtrecht University · NL

Funding

Danone Nutricia ResearchDepartment of Clinical Sciences and Community Health of the University of Milan PSR2015-1719FBRAV
6 · The paper itself

Abstract

(1) Background: Several studies have reported associations between maternal diet in terms of single foods or nutrients and human milk compounds, while the overall role of maternal diet and related dietary patterns has rarely been investigated. (2) Methods: Between 2012 and 2014, we enrolled 300 healthy Italian mothers, who exclusively breastfed their infant. During a hospital visit at 6 weeks postpartum, a sample of freshly expressed foremilk was collected and information on maternal dietary habits in the postpartum period was obtained through an interviewer-administered food frequency questionnaire. We applied principal component factor analysis to selected nutrients in order to identify maternal dietary patterns, and assessed correlations in human milk macronutrients and fatty acids across levels of dietary patterns. (3) Results: Five dietary patterns were identified, named "Vitamins, minerals and fibre", "Proteins and fatty acids with legs", "Fatty acids with fins", "Fatty acids with leaves", "Starch and vegetable proteins". These dietary patterns were correlated with some milk components, namely fatty acids, and in particular ω-3 and its subcomponents. (4) Conclusions: This study showed that overall maternal dietary habits during breastfeeding may influence human milk composition, suggesting the importance of adequate maternal nutrition during lactation not only for the mother herself but also to provide the infant with milk containing adequate amount and quality of nutrients for a balanced nutrition.

Indexed as

Breast FeedingNutrientsNutritional StatusAdultDietDietary FiberFatty Acids, Omega-3Feeding BehaviorFemaleHumansItalyLactationMaternal Nutritional Physiological PhenomenaMilk, HumanMothersPostpartum PeriodDietary FiberFatty Acids, Omega-3Nutrientsdietary patternsfactor analysishuman milkmaternal nutrition breastfeeding

Identifiers

PMID34069630
PMCPMC8160768
OpenAlexW3163954430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.