ArticleBiomolecules2021
Thermal Properties and Structural Features of Multilayer Films Based on Chitosan and Anionic Polysaccharides.
Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 17 citations in OpenAlex.
- Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications.Gels (Basel, Switzerland) · 2023Review
- A Safe-by-Design Approach for the Synthesis of a Novel Cross-Linked Hyaluronic Acid with Improved Biological and Physical Properties.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Article
- Does the Freeze-Thaw Technique Affect the Properties of the Alginate/Chitosan Glutamate Gels with Posaconazole as a Model Antifungal Drug?International journal of molecular sciences · 2022Article
- Chitosan as a Valuable Biomolecule from Seafood Industry Waste in the Design of Green Food Packaging.Biomolecules · 2021Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigates the thermal and structural properties of multilayer composites based on chitosan (CS) and polyanions with different functionalities, including sodium sulfoethyl cellulose (SEC), sodium alginate (ALG), and sodium hyaluronate (HA). Unlike polyelectrolyte complexes (PECs) obtained by polymer mixing, the formation of a PEC layer by a process of layer-by-layer deposition of oppositely charged polymers is accompanied by the transformation of the CS polymorphic state, and this affects the relaxation and thermal properties of the resulting multilayer composite. X-ray diffraction analysis showed that the formation of the PEC layer in the CS/SEC multilayer film is accompanied by crystallization of the CS chains and the formation of a predominantly anhydrous CS modification. Thermogravimetric analysis of the CS/SEC film registers a high-temperature peak associated with the thermal decomposition of crystalline CS in the PEC composition. According to the dynamic mechanical analysis, the CS/SEC composite was characterized by a single glass transition temperature, indicating a strong interaction between the layers when using SEC (a strong acid salt) as the counterion to CS. For multilayer composites with weak polyacid salts (ALG and HA), the crystallization of CS in the PEC layer is weaker, as reflected in the thermal degradation of these films. A high-temperature peak is recorded in the thermal decomposition of CS/HA and is absent in the case of CS/ALG. Dynamic mechanical analysis of the CS/ALG composite showed two glass transition temperatures close to those of the original polymers, indicating weak PEC formation. The CS/HA composite showed an intermediate response. Thus, the effect of the PEC layer on the properties of the poly-layer composites decreases in the order CS/SEC > CS/HA > CS/ALG.
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