Evidence map›Paper›PMID 34069603›Full record

ArticleMedicina (Kaunas, Lithuania)2021

European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): Expert Consensus on the Diagnosis, Service Provision, and Care of People with ME/CFS in Europe.

Luis Nacul, François Jérôme Authier, Carmen Scheibenbogen, Lorenzo Lorusso, Ingrid Bergliot Helland, Jose Alegre Martin, Carmen Adella Sirbu, Anne Marit Mengshoel, Olli Polo, Uta Behrends and 17 more

Registry-linked trialOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05128292 (Role of the NLRP3 Inflammasome Activation, Mitochondrial Biogenesis, and Immunoinflammatory Response After Oral Coenzyme Q10 Plus Selenium Supplementation in Individuals With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome), which is not on this map. Cited by 117 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 4 pooled it
22.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05128292 nacompletednot on this map

Role of the NLRP3 Inflammasome Activation, Mitochondrial Biogenesis, and Immunoinflammatory Response After Oral Coenzyme Q10 Plus Selenium Supplementation in Individuals With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

TypeinterventionalSponsorHospital Universitari Vall d'Hebron Research InstituteRan2018 to 2018Enrolled42ConditionsMyalgic EncephalomyelitisArmsCoQ10 plus Selenium
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 4 syntheses or guidelines pooled it, 190 citations in OpenAlex.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
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  8. Development and Content Validity of the Clinical Needs Assessment for Myalgic Encephalomyelitis (CNAME).Health expectations : an international journal of public participation in health care and health policy · 2026
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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 19 institutions in 17 countries.

Luis NaculLondon School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London WC1E 7HT, UK.
François Jérôme AuthierFaculty of Medicine Créteil-Paris Est, 94010 Creteil, France.
Carmen ScheibenbogenInstitute of Medical Immunology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-8554-9638
Lorenzo LorussoNeurology and Stroke Unit-Neuroscience Department-A.S.S.T.-Lecco, 23900 Merate, Italy.ORCID 0000-0002-5894-8545
Ingrid Bergliot HellandNational Advisory Unit on CFS/ME, Oslo University Hospital, Rikshospitalet OUS, 0372 Oslo, Norway.
Jose Alegre MartinChronic Fatigue Unit, Hospital Universitari Vall d'Hebron University Hospital (VHIR), Universitat Autònoma de Barcelona, E-08035 Barcelona, Spain.
Carmen Adella SirbuCentral Military Emergency University Hospital, Titu Maiorescu University, 040441 Bucharest, Romania.ORCID 0000-0002-1982-1066
Anne Marit MengshoelInstitute of Health and Society, Medical Faculty, University of Oslo, Box 1089 Blindern, 0317 Oslo, Norway.ORCID 0000-0003-1800-4440
Olli PoloBragée ME/CFS Center, 115 26 Stockholm, Sweden.
Uta BehrendsDepartment of Pediatrics, School of Medicine, Technical University of Munich, 80333 Munich, Germany.
Henrik NielsenPrivat Hospitalet Danmark, 2920 Charlottenlund, Denmark.
Patricia GrabowskiDepartment of Hematology, Oncology and Tumor Immunology, Institute for Medical Immunology, Charite Medical School, 10117 Berlin, Germany.
Slobodan SekulicMedical Faculty Novi Sad, University of Novi Sad, 21000 Novi Sad, Serbia.
Nuno SepulvedaCentre of Statistics and Its Applications, University of Lisbon, 1749-016 Lisbon, Portugal.
Fernando Estévez-LópezErasmus MC University Medical Center, 3015 Rotterdam, The Netherlands.ORCID 0000-0003-2960-4142
Pawel ZalewskiDepartment of Hygiene, Epidemiology, Ergonomics and Postgraduate Education, Nicolaus Copernicus University in Torun, Collegium Medicum, 85-067 Bydgoszcz, Poland.ORCID 0000-0001-8453-7785
Derek F H PhebySociety and Health, Buckinghamshire New University (retired), High Wycombe HP11 2JZ, UK.ORCID 0000-0003-1726-0717
Jesus Castro-MarreroDivision of Rheumatology, ME/CFS Research Unit (Lab 009-Box 02), Vall d'Hebron Hospital Research Institute (VHIR), Val d'Hebron Hospital Research Unit (VIHR), Passeig de la Val d'Hebron 119-129, E-08035 Barcelona, Spain.ORCID 0000-0002-2481-3052
Giorgos K SakkasDepartment of PE and Sports Science, University of Thessaly, 421 00 Trikala, Greece.ORCID 0000-0002-2462-995X
Enrica CapelliDepartment of Earth and Environmental Sciences, University of Pavia, 27100 Pavia, Italy.
Ivan BrundsdlundDepartment of Regional Health Research, University Hospital of Southern Denmark, 5000 Odense, Denmark.
John CullinanSchool of Business & Economics, National University of Ireland Galway, University Road, H91 TK33 Galway, Ireland.ORCID 0000-0003-3509-0635
Angelika KruminaDepartment of Infectiology and Dermatology, Riga Stradins University, LV-1067 Riga, Latvia.
Jonas BergquistDepartment of Chemistry-Biomedical Center, Analytical Chemistry and Neuro Chemistry, Uppsala University, 751 23 Uppsala, Sweden.ORCID 0000-0002-4597-041X
Modra MurovskaInstitute of Microbiology and Virology, Riga Stradins University, LV-1067 Riga, Latvia.ORCID 0000-0003-0971-1784
Ruud C W VermuelenCFS/ME Medical Centre, 1078 Amsterdam, The Netherlands.
Eliana M LacerdaDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.ORCID 0000-0002-5077-7868
Charité - Universitätsmedizin Berlin · DERiga Stradiņš University · LVUniversity of London · GBBuckinghamshire New University · GBErasmus MC · NLNicolaus Copernicus University · PLOllscoil na Gaillimhe – University of Galway · IEOslo University Hospital · NOTechnical University of Munich · DETitu Maiorescu University · ROUniversitat Autònoma de Barcelona · ESUniversité Paris-Est Créteil · FRUniversity of Lisbon · PTUniversity of Novi Sad · RSUniversity of Oslo · NOUniversity of Pavia · ITUniversity of Southern Denmark · DKUniversity of Thessaly · GRUppsala University · SE

Funding

A longitudinal immunological and virological study for ME CFS biomarker discovery (Renewal)R01AI103629 · NIAID · LONDON SCH/HYGIENE & TROPICAL MEDICINE · PI DOCKRELL, HAZEL MARGUERITE, NACUL, LUIS · 2013 to 2020
$4.1M
NIAID NIH HHS R01 AI103629
6 · The paper itself

Abstract

Designed by a group of ME/CFS researchers and health professionals, the European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE) has received funding from the European Cooperation in Science and Technology (COST)-COST action 15111-from 2016 to 2020. The main goal of the Cost Action was to assess the existing knowledge and experience on health care delivery for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in European countries, and to enhance coordinated research and health care provision in this field. We report our findings and make recommendations for clinical diagnosis, health services and care for people with ME/CFS in Europe, as prepared by the group of clinicians and researchers from 22 countries and 55 European health professionals and researchers, who have been informed by people with ME/CFS.

Indexed as

Fatigue Syndrome, ChronicConsensusDelivery of Health CareEuropeHumanscarediagnosishealth servicesMyalgic Encephalomyelitis/Chronic Fatigue Syndrome

Identifiers

PMID34069603
PMCPMC8161074
OpenAlexW3160825113

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.