Evidence map›Paper›PMID 34069556›Full record

ArticleBrain sciences2021

Frontotemporal Transcranial Direct Current Stimulation Decreases Serum Mature Brain-Derived Neurotrophic Factor in Schizophrenia.

Ondine Adam, Marion Psomiades, Romain Rey, Nathalie Mandairon, Marie-Francoise Suaud-Chagny, Marine Mondino, Jerome Brunelin

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ondine AdamCentre Hospitalier Le Vinatier, F-69500 Bron, France.ORCID 0000-0001-6311-2796
Marion PsomiadesINSERM U1028, CNRS UMR5292, PSYR2 Team, Lyon Neuroscience Research Center, Université Claude Bernard Lyon 1, Université Jean Monnet, F-69500 Bron, France.
Romain ReyCentre Hospitalier Le Vinatier, F-69500 Bron, France.
Nathalie MandaironCentre Hospitalier Le Vinatier, F-69500 Bron, France.
Marie-Francoise Suaud-ChagnyINSERM U1028, CNRS UMR5292, PSYR2 Team, Lyon Neuroscience Research Center, Université Claude Bernard Lyon 1, Université Jean Monnet, F-69500 Bron, France.
Marine MondinoCentre Hospitalier Le Vinatier, F-69500 Bron, France.ORCID 0000-0003-3175-8503
Jerome BrunelinCentre Hospitalier Le Vinatier, F-69500 Bron, France.ORCID 0000-0001-5479-5628
Université Claude Bernard Lyon 1 · FR

Funding

CSR CH Le Vinatier CSRB04Fondation de l'Avenir pour la Recherche Médicale Appliquée RMA2015
6 · The paper itself

Abstract

Although transcranial direct current stimulation (tDCS) shows promise as a treatment for auditory verbal hallucinations in patients with schizophrenia, mechanisms through which tDCS may induce beneficial effects remain unclear. Evidence points to the involvement of neuronal plasticity mechanisms that are underpinned, amongst others, by brain-derived neurotrophic factor (BDNF) in its two main forms: pro and mature peptides. Here, we aimed to investigate whether tDCS modulates neural plasticity by measuring the acute effects of tDCS on peripheral mature BDNF levels in patients with schizophrenia. Blood samples were collected in 24 patients with schizophrenia before and after they received a single session of either active (20 min, 2 mA,

Indexed as

mature BDNFplasticityschizophreniatDCS

Identifiers

PMID34069556
PMCPMC8160668
OpenAlexW3160403622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.