Evidence map›Paper›PMID 34069466›Full record

ArticleAnimals : an open access journal from MDPI2021

Enteric Viral Infections among Domesticated South American Camelids: First Detection of Mammalian Orthoreovirus in Camelids.

Dayana Castilla, Victor Escobar, Sergio Ynga, Luis Llanco, Alberto Manchego, César Lázaro, Dennis Navarro, Norma Santos, Miguel Rojas

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Molecular detection of zoonotic RNA viruses in guinea pigs (One health (Amsterdam, Netherlands) · 2026
    Article
  2. Article
  3. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dayana CastillaLaboratorio de Inmunología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.
Victor EscobarLaboratorio de Inmunología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.
Sergio YngaLaboratorio de Inmunología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.
Luis LlancoLaboratorio de Zootecnia y Producción Agropecuaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.ORCID 0000-0003-2175-9406
Alberto ManchegoLaboratorio de Inmunología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.
César LázaroLaboratorio de Farmacología y Toxicología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.
Dennis NavarroLaboratorio de Virología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.ORCID 0000-0002-5129-6599
Norma SantosInstituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0002-5123-9172
Miguel RojasLaboratorio de Inmunología, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Apartado 03-5137, Peru.ORCID 0000-0001-5029-3874

Funding

CONCYTEC-FONDECYT en el marco de la convocatoria "Proyecto Investigación Básica 2019-01" 355-2019Vicerrectorado de Investigación y Posgrado de la Universidad Nacional Mayor de San Marcos en el marco de la convocatoria "Proyecto de Investigación con financiamiento para Grupos de Inves-tigación 2021 -PCONFIGI" A21080551
6 · The paper itself

Abstract

Enteric infections are a major cause of neonatal death in South American camelids (SACs). The aim of this study was to determine the prevalence of enteric viral pathogens among alpacas and llamas in Canchis, Cuzco, located in the southern Peruvian highland. Fecal samples were obtained from 80 neonatal alpacas and llamas and tested for coronavirus (CoV), mammalian orthoreovirus (MRV), and rotavirus A (RVA) by RT-PCR. Of the 80 fecal samples analyzed, 76 (95%) were positive for at least one of the viruses tested. Overall, the frequencies of positive samples were 94.1% and 100% among alpacas and llamas, respectively. Of the positive samples, 33 (43.4%) were monoinfected, while 43 (56.6%) had coinfections with two (83.7%) or three (16.3%) viruses. CoV was the most commonly detected virus (87.5%) followed by MRV (50%). RVA was detected only in coinfections. To our knowledge, this is the first description of MRV circulation in SACs or camelids anywhere. These data show that multiple viruses circulate widely among young alpaca and llama crias within the studied areas. These infections can potentially reduce livestock productivity, which translates into serious economic losses for rural communities, directly impacting their livelihoods.

Indexed as

alpacascoronavirusllamasmammalian orthoreovirusPerurotavirus

Identifiers

PMID34069466
PMCPMC8159077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.