Evidence map›Paper›PMID 34069453›Full record

ArticleViruses2021

SARS-CoV-2 Infections and Viral Isolations among Serially Tested Cats and Dogs in Households with Infected Owners in Texas, USA.

Sarah A Hamer, Alex Pauvolid-Corrêa, Italo B Zecca, Edward Davila, Lisa D Auckland, Christopher M Roundy, Wendy Tang, Mia Kim Torchetti, Mary Lea Killian, Melinda Jenkins-Moore and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 1 synthesis or guideline pooled it, 190 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Spike destabilization attenuates Mink Cluster 5 SARS-CoV-2.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Improving the ONE HEALTH approach: a lesson from SARS-CoV-2 pandemic.Journal of preventive medicine and hygiene · 2024
    Review
  20. Review

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Sarah A HamerCollege of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-4955-048X
Alex Pauvolid-CorrêaCollege of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Italo B ZeccaCollege of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-0828-4645
Edward DavilaCollege of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Lisa D AucklandCollege of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Christopher M RoundyDepartment of Entomology, Texas A&M University and AgriLife Research, College Station, TX 77843, USA.
Wendy TangDepartment of Entomology, Texas A&M University and AgriLife Research, College Station, TX 77843, USA.ORCID 0000-0003-0128-1476
Mia Kim TorchettiNational Veterinary Services Laboratories, USDA APHIS VS, Ames, IA 50010, USA.
Mary Lea KillianNational Veterinary Services Laboratories, USDA APHIS VS, Ames, IA 50010, USA.
Melinda Jenkins-MooreNational Veterinary Services Laboratories, USDA APHIS VS, Ames, IA 50010, USA.
Katie MozingoNational Veterinary Services Laboratories, USDA APHIS VS, Ames, IA 50010, USA.
Yao AkpaluBrazos County Health Department, Bryan, TX 77803, USA.
Ria R GhaiNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Jessica R SpenglerNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-5383-0513
Casey Barton BehraveshNational Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Rebecca S B FischerSchool of Public Health, Texas A&M University, College Station, TX 77843, USA.
Gabriel L HamerDepartment of Entomology, Texas A&M University and AgriLife Research, College Station, TX 77843, USA.ORCID 0000-0002-9829-788X
Texas A&M University · USAnimal and Plant Health Inspection Service · USCenters for Disease Control and Prevention · USFundação Oswaldo Cruz · BR

Funding

Consequences of pathogen co-infection in mosquitoes on West Nile virus transmissionK01AI128005 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI HAMER, GABRIEL LEE · 2017 to 2020
$430k
CDC HHS RFP 75D 301-20-R-68167NIAID NIH HHS K01 AI128005Texas A&M AgriLife Research NA
6 · The paper itself

Abstract

Understanding the ecological and epidemiological roles of pets in the transmission of SARS-CoV-2 is critical for animal and human health, identifying household reservoirs, and predicting the potential enzootic maintenance of the virus. We conducted a longitudinal household transmission study of 76 dogs and cats living with at least one SARS-CoV-2-infected human in Texas and found that 17 pets from 25.6% of 39 households met the national case definition for SARS-CoV-2 infections in animals. This includes three out of seventeen (17.6%) cats and one out of fifty-nine (1.7%) dogs that were positive by RT-PCR and sequencing, with the virus successfully isolated from the respiratory swabs of one cat and one dog. Whole-genome sequences of SARS-CoV-2 obtained from all four PCR-positive animals were unique variants grouping with genomes circulating among people with COVID-19 in Texas. Re-sampling showed persistence of viral RNA for at least 25 d-post initial test. Additionally, seven out of sixteen (43.8%) cats and seven out of fifty-nine (11.9%) dogs harbored SARS-CoV-2 neutralizing antibodies upon initial sampling, with relatively stable or increasing titers over the 2-3 months of follow-up and no evidence of seroreversion. The majority (82.4%) of infected pets were asymptomatic. 'Reverse zoonotic' transmission of SARS-CoV-2 from infected people to animals may occur more frequently than recognized.

Indexed as

AnimalsAntibodies, NeutralizingCat DiseasesCatsCOVID-19Dog DiseasesDogsHumansLongitudinal StudiesPetsSARS-CoV-2TexasAntibodies, Neutralizingcatsdogsneutralizing antibodiesreverse zoonosisSARS-CoV-2virus isolation

Identifiers

PMID34069453
PMCPMC8159091
OpenAlexW3162221167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.