Evidence map›Paper›PMID 34069434›Full record

ArticleTropical medicine and infectious disease2021

National Antimicrobial Consumption: Analysis of Central Warehouses Supplies to In-Patient Care Health Facilities from 2017 to 2019 in Uganda.

Juliet Sanyu Namugambe, Alexandre Delamou, Francis Moses, Engy Ali, Veerle Hermans, Kudakwashe Takarinda, Pruthu Thekkur, Stella Maris Nanyonga, Zikan Koroma, Joseph Ngobi Mwoga and 3 more

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juliet Sanyu NamugambeDepartment of Pharmacy, Mbarara University of Science and Technology, Mbarara, P.O. Box 1410 Mbarara, Uganda.
Alexandre DelamouAfrica Centre of Excellence for Prevention and Control of Transmissible Diseases (CEA-PCMT), University Gamal Abdel Nasser, Conakry, PB: 4099 Maferinyah, Guinea.ORCID 0000-0002-9397-7106
Francis MosesMinistry of Health and Sanitation, 00232 Freetown, Sierra Leone.ORCID 0000-0002-9490-6537
Engy AliMédecins Sans Frontières-Operational Centre Brussels, Medical Department, Operational Research Unit (LuxOR), Luxembourg De Manstraat 6, 2100 Deurne, Brussels, Belgium.
Veerle HermansMédecins Sans Frontières-Operational Centre Brussels, Medical Department, Operational Research Unit (LuxOR), Luxembourg De Manstraat 6, 2100 Deurne, Brussels, Belgium.
Kudakwashe TakarindaCentre for Operational Research, International Union Against Tuberculosis and Lung Disease, 75006 Paris, France.
Pruthu ThekkurCentre for Operational Research, International Union Against Tuberculosis and Lung Disease, 75006 Paris, France.ORCID 0000-0001-5257-5074
Stella Maris NanyongaClinical Epidemiology Unit, College of Health Sciences, Makerere University, P.O. Box 7072 Kampala, Uganda.
Zikan KoromaMinistry of Health and Sanitation, 00232 Freetown, Sierra Leone.ORCID 0000-0002-4512-8038
Joseph Ngobi MwogaWorld Health Organisation County Office, P.O. Box 24578 Kampala, Uganda.
Harriet AkelloMinistry of Health Uganda, P.O. Box 7272 Kampala, Uganda.ORCID 0000-0001-5452-4182
Monica ImiEnabel, The Belgian Development Agency, P.O. Box 40131 Kampala, Uganda.
Freddy Eric KitutuSustainable Pharmaceutical Systems (SPS) Unit, Pharmacy Department, School of Health Sciences, Makerere University, P.O. Box 7072, Kampala, Uganda.ORCID 0000-0003-2277-9572

Funding

World Health Organization 001
6 · The paper itself

Abstract

Antimicrobial consumption (AMC) surveillance at global and national levels is necessary to inform relevant interventions and policies. This study analyzed central warehouse antimicrobial supplies to health facilities providing inpatient care in Uganda. We collected data on antimicrobials supplied by National Medical Stores (NMS) and Joint Medical Stores (JMS) to 442 health facilities from 2017 to 2019. Data were analyzed using the World Health Organization methodology for AMC surveillance. Total quantity of antimicrobials in defined daily dose (DDD) were determined, classified into Access, Watch, Reserve (AWaRe) and AMC density was calculated. There was an increase in total DDDs distributed by NMS in 2019 by 4,166,572 DDD. In 2019, Amoxicillin (27%), Cotrimoxazole (20%), and Metronidazole (12%) were the most supplied antimicrobials by NMS while Doxycycline (10%), Amoxicillin (19%), and Metronidazole (10%) were the most supplied by JMS. The majority of antimicrobials supplied by NMS (81%) and JMS (66%) were from the Access category. Increasing antimicrobial consumption density (DDD per 100 patient days) was observed from national referral to lower-level health facilities. Except for NMS in 2019, total antimicrobials supplied by NMS and JMS remained the same from 2017 to 2019. This serves as a baseline for future assessments and monitoring of stewardship interventions.

Indexed as

antimicrobial consumptionantimicrobial resistanceantimicrobialsantimicrobial stewardshipdefined daily doseshealth facilitiesoperational researchSORT-ITUganda

Identifiers

PMID34069434
PMCPMC8163196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.