Evidence map›Paper›PMID 34069265›Full record

ReviewMaterials (Basel, Switzerland)2021

Hard Dental Tissues Regeneration-Approaches and Challenges.

Mihaela Olaru, Liliana Sachelarie, Gabriela Calin

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Editorial: Drug delivery systems for mineralized tissue regeneration.Frontiers in bioengineering and biotechnology · 2026
    Article
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  14. Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mihaela Olaru"Petru Poni" Institute of Macromolecular Chemistry, 41 A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Liliana SachelarieFaculty of Medical Dentistry, "Apollonia" University of Iasi, 2 Muzicii Str., 700399 Iasi, Romania.
Gabriela CalinFaculty of Medical Dentistry, "Apollonia" University of Iasi, 2 Muzicii Str., 700399 Iasi, Romania.ORCID 0000-0002-1893-5109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of the modern concept of tissue engineering approach and the discovery of the potential of stem cells in dentistry, the regeneration of hard dental tissues has become a reality and a priority of modern dentistry. The present review reports the recent advances on stem-cell based regeneration strategies for hard dental tissues and analyze the feasibility of stem cells and of growth factors in scaffolds-based or scaffold-free approaches in inducing the regeneration of either the whole tooth or only of its component structures.

Indexed as

biomaterialsgrowth factorshard dental tissuesscaffold-based and scaffold-free approachstem cellstooth regeneration

Identifiers

PMID34069265
PMCPMC8156070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.