Evidence map›Paper›PMID 34069240›Full record

ReviewJournal of clinical medicine2021

Limited Liver or Lung Colorectal Cancer Metastases. Systemic Treatment, Surgery, Ablation or SBRT.

Meritxell Molla, Julen Fernandez-Plana, Santiago Albiol, Constantino Fondevila, Ivan Vollmer, Carla Cases, Angeles Garcia-Criado, Jaume Capdevila, Carles Conill, Yliam Fundora and 2 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Meritxell MollaDepartment of Radiation Oncology, Hospital Clinic Barcelona, Barcelona 08036, Spain.
Julen Fernandez-PlanaDepartment of Medical Oncology, Hospital Mutua de Terrassa, Terrassa 08221, Spain.
Santiago AlbiolDepartment of Medical Oncology, Hospital Clinic de Barcelona, Barcelona 08036, Spain.
Constantino FondevilaDepartment of General and Digestive Surgery, Hospital Clinic de Barcelona, Barcelona 08036, Spain.ORCID 0000-0002-6161-6824
Ivan VollmerDepartment of Radiology, Hospital Clinic Barcelona, Barcelona 08036, Spain.ORCID 0000-0002-8051-3994
Carla CasesDepartment of Radiation Oncology, Hospital Clinic Barcelona, Barcelona 08036, Spain.ORCID 0000-0003-2110-9016
Angeles Garcia-CriadoDepartment of Radiology, Hospital Clinic Barcelona, Barcelona 08036, Spain.ORCID 0000-0003-3536-4288
Jaume CapdevilaDepartment of Medical Oncology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona 08035, Spain.
Carles ConillDepartment of Radiation Oncology, Hospital Clinic Barcelona, Barcelona 08036, Spain.
Yliam FundoraDepartment of General and Digestive Surgery, Hospital Clinic de Barcelona, Barcelona 08036, Spain.ORCID 0000-0003-4950-6988
Carlos Fernandez-MartosDepartment of Medical Oncology, Instituto Valenciano de Oncología, Valencia 46009, Spain.
Estela PinedaTranslational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona 08036, Spain.ORCID 0000-0003-2128-747X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis for oligometastatic colorectal cancer has improved in recent years, mostly because of recent advances in new techniques and approaches to the treatment of oligometastases, including new surgical procedures, better systemic treatments, percutaneous ablation, and stereotactic body radiation therapy (SBRT). There are several factors to consider when deciding on the better approach for each patient: tumor factors (metachronous or synchronous metastases, RAS mutation, BRAF mutation, disease-free interval, size and number of metastases), patient factors (age, frailty, comorbidities, patient preferences), and physicians' factors (local expertise). These advances have presented major challenges and opportunities for oncologic multidisciplinary teams to treat patients with limited liver and lung metastases from colorectal cancer with a curative intention. In this review, we describe the different treatment options in patients with limited liver and lung metastases from colorectal cancer, and the possible combination of three approaches: systemic treatment, surgery, and local ablative treatments.

Indexed as

ablationcolorectal cancerliver metastaseslung metastasesoligometastasisstereotactic body radiation therapy

Identifiers

PMID34069240
PMCPMC8157146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.