Evidence map›Paper›PMID 34069048›Full record

ArticleBrain sciences2021

Predictive Relevance of Baseline Lactate and Glucose Levels in Patients with Spontaneous Deep-Seated Intracerebral Hemorrhage.

Felix Lehmann, Lorena M Schenk, Matthias Schneider, Joshua D Bernstock, Christian Bode, Valeri Borger, Florian Gessler, Erdem Güresir, Alexis Hadjiathanasiou, Motaz Hamed and 5 more

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Stress hyperglycemia indexes and early neurological deterioration in spontaneous intracerebral hemorrhage.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Felix LehmannDepartment of Anesthesiology and Intensive Care, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-2847-9271
Lorena M SchenkDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.
Matthias SchneiderDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6025-7479
Joshua D BernstockDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Christian BodeDepartment of Anesthesiology and Intensive Care, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-0830-870X
Valeri BorgerDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-5905-4121
Florian GesslerDepartment of Neurosurgery, University Hospital Rostock, 18057 Rostock, Germany.
Erdem GüresirDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-8319-0847
Alexis HadjiathanasiouDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-5477-8518
Motaz HamedDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.
Marcus MüllerDepartment of Neurology, University Hospital Bonn, 53127 Bonn, Germany.
Christian PutensenDepartment of Anesthesiology and Intensive Care, University Hospital Bonn, 53127 Bonn, Germany.
Julian ZimmermannDepartment of Neurology, University Hospital Bonn, 53127 Bonn, Germany.
Hartmut VatterDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.
Patrick SchussDepartment of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-5806-2576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: As elements of the standard admission blood panel, lactate and glucose represent potential biomarkers for outcome prediction. In patients with intracranial hemorrhage (ICH), data on the predictive value of these blood values is exceedingly sparse. (2) Methods: Between 2014 and August 2020, all patients with deep-seated ICH referred to the neurovascular center at the authors' institution were included in the subsequent study. Serum levels of lactate and glucose at the time of admission were compared with mortality at 90 days. In addition, a multivariate analysis was performed in order to identify independent admission predictors for 90-day mortality. (3) Results: Among the 102 patients with deep-seated ICH, elevated lactate and glucose levels on admission were significantly associated with increased mortality at 90 days. Multivariate logistic regression analysis identified "ICH score ≥3" (

Indexed as

glucoseintracerebral hemorrhagelactatemortality

Identifiers

PMID34069048
PMCPMC8156008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.