ArticleJournal of clinical medicine2021
Microcirculation in Patients with Takotsubo Syndrome-The Prospective CIRCUS-TTS Study.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of troponin and natriuretic peptides in Takotsubo syndrome and acute coronary syndrome: a meta-analysis.Open heart · 2024Pooled it
- The role of inflammation in takotsubo syndrome: A new therapeutic target?Journal of cellular and molecular medicine · 2024Review
- Coronary microvascular dysfunction in Takotsubo syndrome and associations with left ventricular function.ESC heart failure · 2023Article
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Broken Heart Syndrome: Evolving Molecular Mechanisms and Principles of Management.Journal of clinical medicine · 2022Review
- Molecular Mechanisms of Takotsubo Syndrome.International journal of molecular sciences · 2022Review
- Takotsubo Syndrome: From Bench to Bedside and Bedside to Bench.Journal of clinical medicine · 2022Article
- Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and Clinical Implications.Circulation · 2022Review
- Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes:Frontiers in cardiovascular medicine · 2022Article
- Coronary Microvascular Dysfunction in Takotsubo Syndrome Assessed by Angiography-Derived Index of Microcirculatory Resistance: A Pressure-Wire-Free Tool.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathophysiology of Takotsubo syndrome (TTS) is incompletely understood. A sympathetic overdrive with coronary microvascular dysfunction might play a central role. The aim of our study was to assess the status of the systemic microcirculation (MC) of patients with TTS, compared to patients with myocardial infarction (MI) and healthy subjects. The systemic microvascular function of 22 TTS patients, 20 patients with MI and 20 healthy subjects was assessed via sublingual sidestream dark-field imaging. In TTS and MI patients, measurements were performed during the acute phase (day 1, 3 and 5) and after 3 months. The measurement in healthy subjects was performed once. The assessed parameters were number of vessel crossings, number of perfused vessel crossings, proportion of perfused vessels, total vessel density and perfused vessel density. The results did not show relevant differences between the investigated groups. Some minor, albeit statistically significant, differences occurred rather randomly. The MC parameters of the TTS group did not show any relevant changes in the temporal course. A systemic microvascular dysfunction could not be identified as a contributing factor in the pathogenesis of TTS. A possible microvascular dysfunction might instead be caused by a local effect restricted to the coronary microvascular bed.
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