Evidence map›Paper›PMID 34069009›Full record

ArticleMolecules (Basel, Switzerland)2021

Optimization of the Biosynthesis of B-Ring

Longji Wang, Xiubing Ma, Haixiang Ruan, Yang Chen, Liping Gao, Ting Lei, Yan Li, Lin Gui, Lina Guo, Tao Xia and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Engineering non-P450 3-hydroxylase forSynthetic and systems biotechnology · 2025
    Article
  2. Efficient production of hydroxysalidroside inSynthetic and systems biotechnology · 2025
    Article
  3. Improvement of the Quality of Wild Rocket (Journal of agricultural and food chemistry · 2024
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Longji WangSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Xiubing MaSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Haixiang RuanSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Yang ChenSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Liping GaoSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Ting LeiSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Yan LiSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Lin GuiSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Lina GuoSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.
Tao XiaState Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, China.
Yunsheng WangSchool of Life Science, Anhui Agricultural University, Hefei 230036, China.ORCID 0000-0002-0348-4608

Funding

National Natural Science Foundation of China no. 31770729the National Key R&D Program of China no. 2018YFD1000601the Natural Science Foundation of China no. 31870676the Natural Science Foundation of China no.31870677
6 · The paper itself

Abstract

Flavonoids are important plant metabolites that exhibit a wide range of physiological and pharmaceutical functions. Because of their wide biological activities, such as anti-inflammatory, antioxidant, antiaging and anticancer, they have been widely used in foods, nutraceutical and pharmaceuticals industries. Here, the hydroxylase complex

Indexed as

BiocatalysisChromatography, High Pressure LiquidEscherichia coliEscherichia coli ProteinsFlavonoidsGenetic EngineeringHydroxylationMixed Function OxygenasesSubstrate SpecificityTemperatureTime FactorsEscherichia coli ProteinsFlavonoidsMixed Function Oxygenases4-hydroxyphenylacetate 3-hydroxylasebiosynthesisB-ring ortho-hydroxylationEscherichia coliflavonoids

Identifiers

PMID34069009
PMCPMC8156182

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.