Evidence map›Paper›PMID 34068980›Full record

ArticleInternational journal of molecular sciences2021

UVB Inhibits Proliferation, Cell Cycle and Induces Apoptosis via p53, E2F1 and Microtubules System in Cervical Cancer Cell Lines.

Angelica Judith Granados-López, Eduardo Manzanares-Acuña, Yamilé López-Hernández, Julio Enrique Castañeda-Delgado, Ixamail Fraire-Soto, Claudia Araceli Reyes-Estrada, Rosalinda Gutiérrez-Hernández, Jesús Adrián López

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Comparative analysis of wavelength-specific UV stress granule formation.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Anti-cancer properties ofFrontiers in oncology · 2022
    Article
  9. Co-Delivery ofFrontiers in pharmacology · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Angelica Judith Granados-LópezLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Campus II, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Zacatecas 98068, Mexico.
Eduardo Manzanares-AcuñaUnidad Académica de Estudios Nucleares, Campus II, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Zacatecas 98068, Mexico.
Yamilé López-HernándezCONACYT, Laboratorio de Metabolómica y Proteómica, Unidad Académica de Ciencias Biológicas, Campus II, Universidad Autónoma de Zacatecas, Av. Preparatoria No.301, Zacatecas 98068, Mexico.ORCID 0000-0002-1068-603X
Julio Enrique Castañeda-DelgadoCatedrático-CONACYT, Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano del Seguro Social, Zacatecas 98000, Mexico.
Ixamail Fraire-SotoLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Campus II, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Zacatecas 98068, Mexico.
Claudia Araceli Reyes-EstradaLaboratorio de Inmunohistoquímica y EOx, MCS de la Unidad Académica de Medicina Humana, Campus Siglo XXI, Universidad Autónoma de Zacatecas, Kilómetro 6, Ejido la Escondida, Zacatecas 98160, Mexico.
Rosalinda Gutiérrez-HernándezLaboratorio de Etnofarmacología Nutrición, Unidad Académica de Enfermería, Campus Siglo XXI, Universidad Autónoma de Zacatecas, Kilómetro 6, Ejido la Escondida, Zacatecas 98160, Mexico.
Jesús Adrián LópezLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Campus II, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Zacatecas 98068, Mexico.ORCID 0000-0001-8012-7041
Universidad Autónoma de Zacatecas "Francisco García Salinas" · MXMexican Social Security Institute · MXSecretaría de Ciencia, Humanidades, Tecnología e Innovación · MX

Funding

PRODEP 2020-2021
6 · The paper itself

Abstract

Ultraviolet (UV) exposure has been linked to skin damage and carcinogenesis, but recently UVB has been proposed as a therapeutic approach for cancer. Herein, we investigated the cellular and molecular effects of UVB in immortal and tumorigenic HPV positive and negative cells. Cells were irradiated with 220.5 to 1102.5 J/m

Indexed as

Ultraviolet RaysApoptosisCell CycleCell ProliferationE2F1 Transcription FactorFemaleGene Expression Regulation, NeoplasticHumansMicrotubulesTumor Cells, CulturedTumor Suppressor Protein p53Uterine Cervical NeoplasmsE2F1 protein, humanE2F1 Transcription FactorTP53 protein, humanTumor Suppressor Protein p53E2F1 expressionimmortal and tumorigenic cellsmicrotubule systemp53 expressionUVB irradiation

Identifiers

PMID34068980
PMCPMC8157236
OpenAlexW3163208095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.