ArticlePathogens (Basel, Switzerland)2021
High Prevalence of Epilepsy in an Onchocerciasis-Endemic Area in Mvolo County, South Sudan: A Door-To-Door Survey.
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Nodding Syndrome: The Need to Strengthen Epilepsy Care in Onchocerciasis-Endemic Areas and to Investigate the Pathogenesis of Onchocerciasis-Associated Epilepsy.The American journal of tropical medicine and hygiene · 2026Article
- Seroprevalence and associated factors ofFrontiers in public health · 2026Article
- Community-directed treatment with ivermectin in Maridi, South Sudan: Impact of an onchocerciasis awareness campaign and bi-annual treatment on therapeutic coverage.PLoS neglected tropical diseases · 2025Article
- A community-based vector control intervention "Slash and Clear" implemented in two onchocerciasis-endemic foci in South Sudan.PLoS neglected tropical diseases · 2025Article
- High epilepsy prevalence and excess mortality in onchocerciasis-endemic counties of South Sudan: A call for integrated interventions.PLoS neglected tropical diseases · 2025Article
- Accelerating onchocerciasis elimination in humanitarian settings: lessons from South Sudan.International health · 2025Article
- Community-based epilepsy care in an onchocerciasis-endemic area: A 3-year cohort study in Mahenge, Tanzania.Epilepsia · 2025Article
- Cameroonian blackflies (Diptera: Simuliidae) harbour a plethora of RNA viruses.Virus evolution · 2025Article
- Epidemiology of epilepsy in Wulu County, an onchocerciasis-endemic area in South Sudan.Heliyon · 2024Article
- Impact of annual community-directed treatment with ivermectin on the incidence of epilepsy in Mvolo, a two-year prospective study.PLoS neglected tropical diseases · 2024Article
- Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed.Infectious diseases of poverty · 2024Article
- Integration of onchocerciasis morbidity management and disability prevention services in the healthcare system in Tanzania: a call for action and recommendations.Tropical diseases, travel medicine and vaccines · 2024Article
- The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan.Research and reports in tropical medicine · 2024Article
- Prevalence of epilepsy in the onchocerciasis endemic middle belt of Ghana after 27 years of mass drug administration with ivermectin.Infectious diseases of poverty · 2023Article
- The onchocerciasis hypothesis of nodding syndrome.PLoS neglected tropical diseases · 2023Article
- Excitatory amino acids, possible causative agents of nodding syndrome in eastern Africa.Tropical medicine and health · 2023Article
- Epidemiology of nodding syndrome in the Greater Mundri area, South Sudan: Prevalence, spatial pattern and environmental risk factors.PLoS neglected tropical diseases · 2022Article
- The Prevalence of Onchocerciasis-Associated Epilepsy in Mundri West and East Counties, South Sudan: A Door-to-Door Survey.Pathogens (Basel, Switzerland) · 2022Article
- Reducing onchocerciasis-associated morbidity in onchocerciasis-endemic foci with high ongoing transmission: a focus on the children.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
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Authors and funding
8 authors at 5 institutions in 5 countries.
Funding
Abstract
In June 2020, a door-to-door household survey was conducted in Mvolo County, an onchocerciasis-endemic area in South Sudan. A total of 2357 households containing 15,699 individuals agreed to participate in the study. Of these, 5046 (32.1%, 95% CI: 31.4-32.9%) had skin itching and 445 (2.8%, 95% CI: 2.6-3.1%) were blind. An epilepsy screening questionnaire identified 813 (5.1%) persons suspected of having epilepsy. Of them, 804 (98.9%) were seen by a medical doctor, and in 798 (98.1%) the diagnosis of epilepsy was confirmed. The overall epilepsy prevalence was 50.8/1000 (95% CI: 47.6-54.4/1000), while the prevalence of nodding syndrome was 22.4/1000 (95% CI: 20.1-24.9/1000). Younger age, being male, skin itching, blindness, and living in a neighbourhood or village close to the Naam River were risk factors for epilepsy. The annual incidence of epilepsy was 82.8/100,000 (95% CI: 44.1-141.6/100,000). Among children 7-9 years old without epilepsy, 34% were Ov16 seropositive, suggesting high ongoing
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