Evidence map›Paper›PMID 34068971›Full record

ReviewBiomedicines2021

Tissue Engineering Through 3D Bioprinting to Recreate and Study Bone Disease.

Adriene Pavek, Christopher Nartker, Maamoon Saleh, Matthew Kirkham, Sana Khajeh Pour, Ali Aghazadeh-Habashi, Jared J Barrott

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Why Animal Experiments Are Still Indispensable in Bone Research: A Statement by the European Calcified Tissue Society.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Review
  5. Review
  6. Review
  7. Review
  8. Rapid Fabrication of MgNHBiomedicines · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adriene PavekDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.
Christopher NartkerDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.
Maamoon SalehWhitman College, Walla Walla, WA 99362, USA.
Matthew KirkhamDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.
Sana Khajeh PourDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.ORCID 0000-0001-5370-0324
Ali Aghazadeh-HabashiDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.ORCID 0000-0003-4456-3123
Jared J BarrottDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA.ORCID 0000-0001-6059-9009
Idaho State University · USWhitman College · US

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Scott A Minnich · 2012 to 2026
$59.8M
Elsa U. Pardee Foundation 2020 Research GrantIdaho State University Career Pathway InternshipNIGMS NIH HHS P20 GM103408NIH HHS P20 GM103408Whitman College Undergraduate Internship
6 · The paper itself

Abstract

The applications of 3D bioprinting are becoming more commonplace. Since the advent of tissue engineering, bone has received much attention for the ability to engineer normal bone for tissue engraftment or replacement. While there are still debates on what materials comprise the most durable and natural replacement of normal tissue, little attention is given to recreating diseased states within the bone. With a better understanding of the cellular pathophysiology associated with the more common bone diseases, these diseases can be scaled down to a more throughput way to test therapies that can reverse the cellular pathophysiology. In this review, we will discuss the potential of 3D bioprinting of bone tissue in the following disease states: osteoporosis, Paget's disease, heterotopic ossification, osteosarcoma, osteogenesis imperfecta, and rickets disease. The development of these 3D bioprinted models will allow for the advancement of novel therapy testing resulting in possible relief to these chronic diseases.

Indexed as

3D bioprintingboneheterotopic ossificationosteogenesis imperfectaosteoporosisosteosarcomaPaget’s diseaserickets disease

Identifiers

PMID34068971
PMCPMC8156159
OpenAlexW3160212274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.