Evidence map›Paper›PMID 34068955›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Hepatitis C Micro-Elimination beyond Prison Walls: Navigator-Assisted Test-and-Treat Strategy for Subjects Serving Non-Custodial Sentences.

Joaquin Cabezas, Susana Llerena, Miguel Mateo, Rocío Álvarez, Carmen Cobo, Victoria González, Elisa Martró, Antonio Cuadrado, Javier Crespo

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Prevalence and risk factors of active hepatitis C infection among at-risk migrant populations in Madrid, Spain, 2019 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
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  16. Real-life experience of hepatitis C treatment in a Spanish prison.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Observational
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joaquin CabezasGastroenterology and Hepatology Department, University Hospital Marques de Valdecilla, Research Institute Valdecilla (IDIVAL in Spanish), 39008 Santander, Spain.ORCID 0000-0003-0012-484X
Susana LlerenaGastroenterology and Hepatology Department, University Hospital Marques de Valdecilla, Research Institute Valdecilla (IDIVAL in Spanish), 39008 Santander, Spain.
Miguel MateoMedical Department, "José Hierro" Social Integration Unit Health Centre, 39011 Santander, Spain.
Rocío ÁlvarezMedical Department, "José Hierro" Social Integration Unit Health Centre, 39011 Santander, Spain.
Carmen CoboMedical Service, "El Dueso" Penitentiary Centre, 39740 Santoña, Spain.
Victoria GonzálezCentre of Epidemiological Studies of HIV/AIDS and STI of Catalonia (CEEISCAT)-Catalan Institute of Oncology (ICO)-Public Health Agency of Catalonia (ASPCAT), 08005 Badalona, Spain.
Elisa MartróMicrobiology Department, Laboratori Clínic Metropolitana Nord, Hospital Universitari Germans Trias i Pujol, Germans Trias i Pujol Research Institute (IGTP), 08916 Badalona, Spain.
Antonio CuadradoGastroenterology and Hepatology Department, University Hospital Marques de Valdecilla, Research Institute Valdecilla (IDIVAL in Spanish), 39008 Santander, Spain.ORCID 0000-0002-1363-864X
Javier CrespoGastroenterology and Hepatology Department, University Hospital Marques de Valdecilla, Research Institute Valdecilla (IDIVAL in Spanish), 39008 Santander, Spain.

Funding

Gilead Sciences IN-ES-987-5451 / ISR-ES-18-10542
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe Spanish prison population includes two groups: people in prison and those who are serving non-custodial sentences. The latter has not yet been studied. This study aims to describe this population and the results of a test-and-treat strategy for hepatitis C including a holistic health assessment.

methodThis prospective study included all subjects serving non-custodial sentences at the Center for Social Integration. It was assisted by the medical team, a navigator, and a systematic screening of HCV (Hepatitis C Virus) performed by point-of-care tests. All cases with active infection are evaluated using telemedicine by a specialist to prescribe antiviral treatment. The navigator facilitates continuity for medical and social assistance.

resultsThe screening rate reached 92.8% (548/590). HCV seroprevalence and viraemia prevalence were 8% (44) and 2.9% (16), respectively. Regarding comorbidities: problems related to drug dependence were detected in 264 (48.2%), suspected serious mental disorder in 44 (8.3%), and previous stay in prison in 122 cases (22.2%). The navigator monitored 59 (15.2%) patients regarding HCV treatment or comorbidities. All patients (10/10) completing 12 weeks follow-up achieved sustained virological response.

conclusionsThe population serving non-custodial sentences is a challenging group with a high prevalence of HCV infection. Micro-elimination programs using point of care diagnostic tests, telemedicine, and a navigator are necessary in this underserved vulnerable population.

Indexed as

community sentencescorrectional settinghepatitis Cnavigatorpoint-of-care testunderserved

Identifiers

PMID34068955
PMCPMC8155928

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.