Evidence map›Paper›PMID 34068920›Full record

ArticleMolecules (Basel, Switzerland)2021

A Concise Synthesis of a BODIPY-Labeled Tetrasaccharide Related to the Antitumor PI-88.

Juan Ventura, Clara Uriel, Ana M Gomez, Edurne Avellanal-Zaballa, Jorge Bañuelos, Inmaculada García-Moreno, Jose Cristobal Lopez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Juan VenturaInstituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-2240-1839
Clara UrielInstituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-4598-7438
Ana M GomezInstituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-8703-3360
Edurne Avellanal-ZaballaDepartamento de Química Física, Universidad del Pais Vasco-EHU, Apartado 644, 48080 Bilbao, Spain.
Jorge BañuelosDepartamento de Química Física, Universidad del Pais Vasco-EHU, Apartado 644, 48080 Bilbao, Spain.ORCID 0000-0002-8444-4383
Inmaculada García-MorenoInstituto de Química-Física "Rocasolano", IQFR-CSIC, Serrano 119, 28006 Madrid, Spain.
Jose Cristobal LopezInstituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-0370-4727
Instituto de Química Orgánica General · ESUniversity of the Basque Country · ESInstituto de Química Física Blas Cabrera · ES

Funding

Gobierno Vasco IT912-16Ministerio de Ciencia, Innovación y Universidades RTI2018-094862-B-I00Ministerio de Economia y Competitividad, Gobierno de España CTQ2015-66702-RMinisterio de Economia y Competitividad, Gobierno de España MAT2017-83856-C3-1-P and 3-P
6 · The paper itself

Abstract

A convergent synthetic route to a tetrasaccharide related to PI-88, which allows the incorporation of a fluorescent BODIPY-label at the reducing-end, has been developed. The strategy, which features the use of 1,2-methyl orthoesters (MeOEs) as glycosyl donors, illustrates the usefulness of suitably-designed BODIPY dyes as glycosyl labels in synthetic strategies towards fluorescently-tagged oligosaccharides.

Indexed as

Staining and LabelingAntineoplastic AgentsBoron CompoundsGlycosylationOligosaccharidesSpectrometry, FluorescenceStereoisomerism4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneAntineoplastic AgentsBoron CompoundsOligosaccharidesphosphomannopentaose sulfate1,2-methyl orthoestersBODIPYfluorescent labelingglycosylationPI-88

Identifiers

PMID34068920
PMCPMC8156587
OpenAlexW3162444558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.