Evidence map›Paper›PMID 34068868›Full record

ReviewGels (Basel, Switzerland)2021

Nanoclay/Polymer-Based Hydrogels and Enzyme-Loaded Nanostructures for Wound Healing Applications.

Angel M Villalba-Rodríguez, Sara Martínez-González, Juan Eduardo Sosa-Hernández, Roberto Parra-Saldívar, Muhammad Bilal, Hafiz M N Iqbal

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Angel M Villalba-RodríguezTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.
Sara Martínez-GonzálezTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.
Juan Eduardo Sosa-HernándezTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0001-5441-4768
Roberto Parra-SaldívarTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0002-4958-5797
Muhammad BilalSchool of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.ORCID 0000-0001-5388-3183
Hafiz M N IqbalTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0003-4855-2720

Funding

Consejo Nacional de Ciencia y Tecnología 795810
6 · The paper itself

Abstract

Multi-polymeric nanocomposite hydrogels with multi-functional characteristics have been engineered with high interest around the globe. The ease in fine tunability with maintained compliance makes an array of nanocomposite biomaterials outstanding candidates for the biomedical sector of the modern world. In this context, the present work intends to tackle the necessity of alternatives for the treatment of diabetic foot ulcers through the formulation of nanoclay and/or polymer-based nanocomposite hydrogels. Laponite RD, a synthetic 2-D nanoclay that becomes inert when in a physiological environment, while mixed with water, becomes a clear gel with interesting shear-thinning properties. Adding Laponite RD to chitosan or gelatin allows for the modification of the mechanical properties of such materials. The setup explored in this research allows for a promising polymeric matrix that can potentially be loaded with active compounds for antibacterial support in foot ulcers, as well as enzymes for wound debridement.

Indexed as

biomedicalchitosanhydrogelslaponitenanoparticlespolymeric materialswound healing

Identifiers

PMID34068868
PMCPMC8162325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.