Evidence map›Paper›PMID 34068769›Full record

ArticleJournal of personalized medicine2021

Targeting Lyn Kinase in Chorea-Acanthocytosis: A Translational Treatment Approach in a Rare Disease.

Kevin Peikert, Hannes Glaß, Enrica Federti, Alessandro Matte, Lisann Pelzl, Katja Akgün, Tjalf Ziemssen, Rainer Ordemann, Florian Lang, The Network For Translational Research For Neuroacanthocytosis Patients and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Yeast as a Model to Find New Drugs and Drug Targets forInternational journal of molecular sciences · 2022
    Review
  5. XK-Associated McLeod Syndrome: Nonhematological Manifestations and Relation to VPS13A Disease.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Neuroacanthocytosis Syndromes: The Clinical Perspective.Contact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Kevin PeikertDepartment of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0002-0845-2453
Hannes GlaßDepartment of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Enrica FedertiDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Alessandro MatteDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Lisann PelzlDepartment of Physiology I, University of Tübingen, 72076 Tübingen, Germany.
Katja AkgünDepartment of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Tjalf ZiemssenDepartment of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0001-8799-8202
Rainer OrdemannMedical Department I, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01069 Dresden, Germany.
Florian LangDepartment of Physiology I, University of Tübingen, 72076 Tübingen, Germany.
The Network For Translational Research For Neuroacanthocytosis Patients
Lucia De FranceschiDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Andreas HermannDepartment of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0002-7364-7791
University Hospital Carl Gustav Carus · DEUniversity of Verona · ITUniversity of Tübingen · DEGerman Center for Neurodegenerative Diseases · DE

Funding

Else Kröner-Fresenius-Stiftung Clinician Scientist Program (TU Dresden)
6 · The paper itself

Abstract

Chorea-acanthocytosis (ChAc) is a neurodegenerative disease caused by mutations in the

Indexed as

ChAcdasatinibneuroacanthocytosisoff-labelTKI

Identifiers

PMID34068769
PMCPMC8150322
OpenAlexW3138078714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.