Evidence map›Paper›PMID 34068718›Full record

ArticleChildren (Basel, Switzerland)2021

Predicting Treatment Outcomes Using Explainable Machine Learning in Children with Asthma.

Mario Lovrić, Ivana Banić, Emanuel Lacić, Kristina Pavlović, Roman Kern, Mirjana Turkalj

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Early predictors of persistent childhood asthma and allergic rhinitis: A machine learning study using post-hoc explainability.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. AI model for predicting asthma prognosis in children.The journal of allergy and clinical immunology. Global · 2025
    Article
  7. Artificial intelligence in pediatric allergy research.European journal of pediatrics · 2024
    Review
  8. Article
  9. Article
  10. Persistent Asthma in Childhood.Children (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Prediction Models of Early Childhood Caries Based on Machine Learning Algorithms.International journal of environmental research and public health · 2021
    Article
  13. Article
  14. Prediction of Type 2 Diabetes Based on Machine Learning Algorithm.International journal of environmental research and public health · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mario LovrićKnowledge Discovery, Know-Center, Infeldgasse 13, 8010 Graz, Austria.ORCID 0000-0002-3541-9624
Ivana BanićSrebrnjak Children's Hospital, Srebrnjak 100, 10000 Zagreb, Croatia.
Emanuel LacićKnowledge Discovery, Know-Center, Infeldgasse 13, 8010 Graz, Austria.ORCID 0000-0002-3059-0502
Kristina PavlovićKnowledge Discovery, Know-Center, Infeldgasse 13, 8010 Graz, Austria.ORCID 0000-0001-6069-7020
Roman KernKnowledge Discovery, Know-Center, Infeldgasse 13, 8010 Graz, Austria.ORCID 0000-0003-0202-6100
Mirjana TurkaljSrebrnjak Children's Hospital, Srebrnjak 100, 10000 Zagreb, Croatia.ORCID 0000-0002-5339-861X
Know Center Research GmbH (Austria) · ATChildren's Hospital Srebrnjak · HRGraz University of Technology · AT

Funding

Österreichische Forschungsförderungsgesellschaft n/a
6 · The paper itself

Abstract

Asthma in children is a heterogeneous disease manifested by various phenotypes and endotypes. The level of disease control, as well as the effectiveness of anti-inflammatory treatment, is variable and inadequate in a significant portion of patients. By applying machine learning algorithms, we aimed to predict the treatment success in a pediatric asthma cohort and to identify the key variables for understanding the underlying mechanisms. We predicted the treatment outcomes in children with mild to severe asthma (

Indexed as

asthma controlasthma controller medicationchildhood asthmamachine learningtreatment outcome

Identifiers

PMID34068718
PMCPMC8151683
OpenAlexW3160052398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.