Evidence map›Paper›PMID 34068605›Full record

ReviewMedicina (Kaunas, Lithuania)2021

ADHD and Bipolar Disorder in Adulthood: Clinical and Treatment Implications.

Virginio Salvi, Enrico Ribuoli, Michele Servasi, Laura Orsolini, Umberto Volpe

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. ADHD symptom trajectories across childhood and early adolescence and risk for hypomanic symptoms in young adulthood.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Observational
  14. Article
  15. Research progress of tDCS in the treatment of ADHD.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Virginio SalviUnit of Clinical Psychiatry, Ospedali Riuniti, 60100 Ancona, Italy.ORCID 0000-0003-3374-018X
Enrico RibuoliDepartment of Clinical Neurosciences/DIMSC, Università Politecnica delle Marche, 60121 Ancona, Italy.
Michele ServasiUnit of Clinical Psychiatry, Ospedali Riuniti, 60100 Ancona, Italy.
Laura OrsoliniUnit of Clinical Psychiatry, Ospedali Riuniti, 60100 Ancona, Italy.ORCID 0000-0002-6882-3770
Umberto VolpeUnit of Clinical Psychiatry, Ospedali Riuniti, 60100 Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit hyperactivity disorder (ADHD) is a condition that usually has its onset in childhood. Although the disorder persists into adulthood in half of cases, adult ADHD is often not recognized due to different psychopathological characteristics, quite often overlapping with other diagnoses such as mood, anxiety and personality disorders. This is especially true for bipolar disorder (BD), which shares several symptoms with adult ADHD. Moreover, besides an overlapping clinical presentation, BD is often co-occurring in adults with ADHD, with comorbidity figures as high as 20%. This review will focus on the comorbidity between ADHD and BD by exploring the magnitude of the phenomenon and evaluating the clinical and functional characteristics associated with ADHD-BD comorbidity in adults. Finally, the review will address the implications of pharmacologically treating the ADHD-BD comorbidity, providing suggestions in how to treat these complex patients and addressing the issue of treatment-induced manic switch with the use of stimulants and other medications for ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityBipolar DisorderAdultAnxietyComorbidityHumansADHDbipolar disordercomorbiditystimulantstreatment-induced mania

Identifiers

PMID34068605
PMCPMC8151516

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.