Evidence map›Paper›PMID 34068568›Full record

ArticleMolecules (Basel, Switzerland)2021

Iridin Induces G2/M Phase Cell Cycle Arrest and Extrinsic Apoptotic Cell Death through PI3K/AKT Signaling Pathway in AGS Gastric Cancer Cells.

Pritam-Bhagwan Bhosale, Preethi Vetrivel, Sang-Eun Ha, Hun-Hwan Kim, Jeong-Doo Heo, Chung-Kil Won, Seong-Min Kim, Gon-Sup Kim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  8. [Prognostic Value of PCMT1 Expression in Gastric Cancer and Its Regulatory Effect on Spindle Assembly Checkpoints].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pritam-Bhagwan BhosaleResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.ORCID 0000-0003-1691-7844
Preethi VetrivelResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Sang-Eun HaResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Hun-Hwan KimResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Jeong-Doo HeoBiological Resources Research Group, Bioenvironmental Science & Toxicology Division, Korea Institute of Toxicology (KIT), 17 Jeigok-gil, Jinju 52834, Korea.
Chung-Kil WonResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Seong-Min KimResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Gon-Sup KimResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Gazwa, Jinju 52828, Korea.
Gyeongsang National University · KRKorea Institute of Toxicology · KR

Funding

National Research Foundation of Korea funded by Ministry of Science and ICT grant no. 2020R1A2B5B01001807
6 · The paper itself

Abstract

Iridin is a natural flavonoid found in

Indexed as

Signal TransductionApoptosisCell Line, TumorCell ProliferationCell SurvivalFlavonoidsG2 Phase Cell Cycle CheckpointsHumansModels, BiologicalM Phase Cell Cycle CheckpointsNeoplasm ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktStomach NeoplasmsFlavonoidsiridinNeoplasm ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktextrinsic apoptosisflavonoidgastric canceriridinPI3K/AKT pathway

Identifiers

PMID34068568
PMCPMC8126061
OpenAlexW3161672039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.