Evidence map›Paper›PMID 34068565›Full record

ArticleMolecules (Basel, Switzerland)2021

Chinese Propolis Suppressed Pancreatic Cancer Panc-1 Cells Proliferation and Migration via Hippo-YAP Pathway.

Lingchen Tao, Xi Chen, Yufei Zheng, Yuqi Wu, Xiasen Jiang, Mengmeng You, Shanshan Li, Fuliang Hu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Apoptosis in Type 2 Diabetes: Can It Be Prevented? Hippo Pathway Prospects.International journal of molecular sciences · 2022
    Review
  11. Review
  12. An Insight into Anticancer Effect of Propolis and Its Constituents: A Review of Molecular Mechanisms.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lingchen TaoCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Xi ChenCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Yufei ZhengCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Yuqi WuCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Xiasen JiangCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Mengmeng YouCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Shanshan LiCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Fuliang HuCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Zhejiang University · CN

Funding

Earmarked Fund for Modern Agro-industry Technology Research System CARS-44
6 · The paper itself

Abstract

Pancreatic cancer is one of the most malignant cancers with high mortality. Therefore, it is of great urgency to develop new agents that could improve the prognosis of Pancreatic cancer patients. Chinese propolis (CP), a flavonoid-rich beehive product, has been reported to have an anticancer effect. In this study, we applied CP to the human Pancreatic cancer cell line Panc-1 to verify its impact on tumor development. CP induced apoptosis in Panc-1 cells from 12.5 µg/mL in a time- and dose-dependent manner with an IC

Indexed as

Adaptor Proteins, Signal TransducingAntineoplastic AgentsCell Cycle CheckpointsCell DeathCell Line, TumorCell MovementCell ProliferationCell SurvivalChromatography, High Pressure LiquidEpithelial-Mesenchymal TransitionHippo Signaling PathwayHumansPancreatic NeoplasmsPropolisProtein Serine-Threonine KinasesReference StandardsAdaptor Proteins, Signal TransducingAntineoplastic AgentsPropolisProtein Serine-Threonine KinasesTranscription FactorsYAP1 protein, humanYAP-Signaling Proteinsapoptosiscell cycle arrestChinese propolisHippo-YAP pathwaymigrationpancreatic cancer

Identifiers

PMID34068565
PMCPMC8126155
OpenAlexW3160554178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.