Evidence map›Paper›PMID 34068525›Full record

ReviewInternational journal of molecular sciences2021

In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function.

Thayza Martins Melzer, Luana Meller Manosso, Suk-Yu Yau, Joana Gil-Mohapel, Patricia S Brocardo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  9. The nutrition toolbox permitsBioinformatics advances · 2026
    Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Thayza Martins MelzerNeuroscience Graduate Program, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Luana Meller ManossoTranslational Psychiatry Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma 88806-000, SC, Brazil.
Suk-Yu YauDepartment of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Joana Gil-MohapelDivision of Medical Sciences, University of Victoria, Victoria, BC V8P 5C2, Canada.ORCID 0000-0003-4982-1662
Patricia S BrocardoNeuroscience Graduate Program, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Universidade Federal de Santa Catarina · BRHong Kong Polytechnic University · HKUniversidade do Sul de Santa Catarina · BRUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consuming a balanced, nutritious diet is important for maintaining health, especially as individuals age. Several studies suggest that consuming a diet rich in antioxidants and anti-inflammatory components such as those found in fruits, nuts, vegetables, and fish may reduce age-related cognitive decline and the risk of developing various neurodegenerative diseases. Numerous studies have been published over the last decade focusing on nutrition and how this impacts health. The main objective of the current article is to review the data linking the role of diet and nutrition with aging and age-related cognitive decline. Specifically, we discuss the roles of micronutrients and macronutrients and provide an overview of how the gut microbiota-gut-brain axis and nutrition impact brain function in general and cognitive processes in particular during aging. We propose that dietary interventions designed to optimize the levels of macro and micronutrients and maximize the functioning of the microbiota-gut-brain axis can be of therapeutic value for improving cognitive functioning, particularly during aging.

Indexed as

AntioxidantsBrainCognitive DysfunctionFruitGastrointestinal MicrobiomeHealthy AgingHumansMicronutrientsNutritional StatusNutrition AssessmentNutsVegetablesAntioxidantsMicronutrientsagingcognitionmacronutrientsmicrobiota-gut-brain axismicronutrientsneurodegenerationnutrition

Identifiers

PMID34068525
PMCPMC8126018
OpenAlexW3163808946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.