Evidence map›Paper›PMID 34068519›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of

Jean Claude Didelot Tomani, Olivier Bonnet, Alain Nyirimigabo, William Deschamps, Alembert Tiabou Tchinda, Olivia Jansen, Allison Ledoux, Marie Jeanne Mukazayire, Luc Vanhamme, Michel Frédérich and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antiplasmodial, Antioxidant, and Cytotoxic Activity ofBioMed research international · 2023
    Article
  5. Leaf hydroalcoholic extract and oleoresin fromFrontiers in cellular and infection microbiology · 2023
    Article
  6. NaMolecules (Basel, Switzerland) · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Jean Claude Didelot TomaniSchool of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.
Olivier BonnetCentre for Interdisciplinary Research on Medicines (CIRM), Laboratory of Pharmacognosy, University of Liège, B36, 4000 Liège, Belgium.ORCID 0000-0003-0350-6640
Alain NyirimigaboSchool of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.ORCID 0000-0002-4731-6497
William DeschampsDepartment of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.ORCID 0000-0002-5334-9383
Alembert Tiabou TchindaLaboratory of Phytochemistry, Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé P.O. Box 13033, Cameroon.
Olivia JansenCentre for Interdisciplinary Research on Medicines (CIRM), Laboratory of Pharmacognosy, University of Liège, B36, 4000 Liège, Belgium.
Allison LedouxCentre for Interdisciplinary Research on Medicines (CIRM), Laboratory of Pharmacognosy, University of Liège, B36, 4000 Liège, Belgium.ORCID 0000-0002-4052-6336
Marie Jeanne MukazayireSchool of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.
Luc VanhammeDepartment of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.
Michel FrédérichCentre for Interdisciplinary Research on Medicines (CIRM), Laboratory of Pharmacognosy, University of Liège, B36, 4000 Liège, Belgium.ORCID 0000-0002-0770-9990
Raymond MugangaSchool of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.
Jacob SouopguiDepartment of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.ORCID 0000-0003-1526-4431
University of Liège · BEUniversité Libre de Bruxelles · BEUniversity of Rwanda · RWInstitut de Recherches Médicales et d’Etudes des Plantes Médicinales · CM

Funding

Académie de recherche et d'enseignement supérieur ARES-PRD2015 to M.F.
6 · The paper itself

Abstract

Malaria remains one of the leading causes of death in sub-Saharan Africa, ranked in the top three infectious diseases in the world. Plants of the

Indexed as

AntimalarialsCell DeathChloroquineComplex MixturesFabaceaeHumansPlant RootsPlasmodium falciparumTHP-1 CellsAntimalarialsChloroquineComplex Mixturesantiplasmodial activitycytotoxicityEriosema montanumisolationmalariapure compoundsTHP-1

Identifiers

PMID34068519
PMCPMC8125995
OpenAlexW3160265491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.