Evidence map›Paper›PMID 34068442›Full record

ArticleInternational journal of molecular sciences2021

Role of Glycated High Mobility Group Box-1 in Gastric Cancer.

Shingo Kishi, Yukiko Nishiguchi, Kanya Honoki, Shiori Mori, Rina Fujiwara-Tani, Takamitsu Sasaki, Kiyomu Fujii, Isao Kawahara, Kei Goto, Chie Nakashima and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Energy metabolism: a new target for gastric cancer treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  6. Circulating Proteins as Diagnostic Markers in Gastric Cancer.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Shingo KishiDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Yukiko NishiguchiDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Kanya HonokiDepartment of Orthopedics, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
Shiori MoriDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Rina Fujiwara-TaniDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Takamitsu SasakiDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Kiyomu FujiiDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Isao KawaharaDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Kei GotoDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Chie NakashimaDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Akira KidoDepartment of Orthopedics, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
Yasuhito TanakaDepartment of Orthopedics, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.ORCID 0000-0002-2300-611X
Yi LuoDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.
Hiroki KuniyasuDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan.ORCID 0000-0003-2298-8825
Nara Medical University · JPNantong University · CN

Funding

MEXT KAKENHI 19K16564MEXT KAKENHI 20K19349MEXT KAKENHI 20K21659National Natural Science Foundation of China 81702723Natural Science Foundation of Jiangsu Education Department Project 17KJB320010
6 · The paper itself

Abstract

Advanced glycation end products (AGEs) are produced in response to a high-glucose environment and oxidative stress and exacerbate various diseases.

Indexed as

Gene Expression Regulation, NeoplasticApoptosisBiomarkers, TumorCell MovementCell ProliferationGlycation End Products, AdvancedGlycosylationHMGB1 ProteinHumansPrognosisReceptor for Advanced Glycation End ProductsStomach NeoplasmsTumor Cells, CulturedBiomarkers, TumorGlycation End Products, AdvancedHMGB1 ProteinHMGB1 protein, humanReceptor for Advanced Glycation End Productsgastric cancerglycationHMGB1Nε-(Carboxymethyl)lysine

Identifiers

PMID34068442
PMCPMC8153607
OpenAlexW3161606958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.