Evidence map›Paper›PMID 34068366›Full record

ArticleInternational journal of molecular sciences2021

Identification of Pyruvate Dehydrogenase E1 as a Potential Target against

Yuejuan Li, Baichun Hu, Zhibin Wang, Jianhua He, Yaoliang Zhang, Jian Wang, Lijie Guan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. The antifungal and antibiofilm effects of isobavachalcone onFrontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuejuan LiDepartment of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Baichun HuKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110142, China.
Zhibin WangDepartment of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Jianhua HeDepartment of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Yaoliang ZhangKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110142, China.
Jian WangKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110142, China.ORCID 0000-0002-9589-4056
Lijie GuanDepartment of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.ORCID 0000-0001-8813-8087
Shenyang University of Chemical Technology · CNShenyang Pharmaceutical University · CN

Funding

Program for Innovative Talents of Higher Education of Liaoning 2012520005Project for National Key Research and Development SQ2020YFF0411744The Overseas Expertise Introduction Project for Discipline Innovation D20029
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChalconesFungal ProteinsFungicides, IndustrialGene Expression ProfilingGene Expression Regulation, FungalMagnaportheMolecular Docking SimulationOryzaPlant DiseasesProtein ConformationPyruvate Dehydrogenase (Lipoamide)TranscriptomeChalconesFungal ProteinsFungicides, IndustrialisobavachalconePyruvate Dehydrogenase (Lipoamide)enzyme activityhomology modelingisobavachalconemolecular dynamics simulationpyruvate dehydrogenaseRNA sequencing

Identifiers

PMID34068366
PMCPMC8153330
OpenAlexW3163011298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.