Evidence map›Paper›PMID 34068353›Full record

ReviewNutrients2021

Dietary Fibre Modulates the Gut Microbiota.

Peter Cronin, Susan A Joyce, Paul W O'Toole, Eibhlís M O'Connor

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 370 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
370citing papers in PubMed, 3 pooled it
46.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

370 citing papers in PubMed, 3 syntheses or guidelines pooled it, 599 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

310 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peter CroninDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Susan A JoyceAPC Microbiome Ireland, University College Cork, T12 K8AF Cork, Ireland.ORCID 0000-0003-4771-3123
Paul W O'TooleAPC Microbiome Ireland, University College Cork, T12 K8AF Cork, Ireland.
Eibhlís M O'ConnorDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
University College Cork · IEUniversity of Limerick · IE

Funding

Department of Agriculture, Food and the Marine, Ireland 17F251
6 · The paper itself

Abstract

Dietary fibre has long been established as a nutritionally important, health-promoting food ingredient. Modern dietary practices have seen a significant reduction in fibre consumption compared with ancestral habits. This is related to the emergence of low-fibre "Western diets" associated with industrialised nations, and is linked to an increased prevalence of gut diseases such as inflammatory bowel disease, obesity, type II diabetes mellitus and metabolic syndrome. The characteristic metabolic parameters of these individuals include insulin resistance, high fasting and postprandial glucose, as well as high plasma cholesterol, low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Gut microbial signatures are also altered significantly in these cohorts, suggesting a causative link between diet, microbes and disease. Dietary fibre consumption has been hypothesised to reverse these changes through microbial fermentation and the subsequent production of short-chain fatty acids (SCFA), which improves glucose and lipid parameters in individuals who harbour diseases associated with dysfunctional metabolism. This review article examines how different types of dietary fibre can differentially alter glucose and lipid metabolism through changes in gut microbiota composition and function.

Indexed as

Dietary FiberFatty Acids, VolatileGastrointestinal MicrobiomeGlucoseHumansLipid MetabolismDietary FiberFatty Acids, VolatileGlucosedietary fibreglucose metabolismlipid metabolismmetabolic healthmetabolic syndromemicrobiotaobesitytype II diabetes mellitus

Identifiers

PMID34068353
PMCPMC8153313
OpenAlexW3161441621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.