ReviewInternational journal of molecular sciences2021
Focus on the Primary Prevention of Intrauterine Adhesions: Current Concept and Vision.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 105 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intrauterine Adhesions Prevention: the Use of Heparin Solution Compared to Application of Anti-adhesion Barrier Gel After Operative Hysteroscopy
Effects of Repeated Propofol Intravenous Anesthesia on the Postoperative Neurological Function of Patients Undergoing Hysteroscopic Surgery: A Prospective Cohort Study
Who cites it
105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- The effectiveness of stem cell‑derived extracellular vesicles therapy for intrauterine adhesions: a meta-analysis of preclinical studies.Reproductive biology and endocrinology : RB&E · 2025Pooled it
- Intrauterine interventions options for preventing recurrence after hysteroscopic adhesiolysis: a systematic review and network meta-analysis of randomized controlled trials.Archives of gynecology and obstetrics · 2024Pooled it
- Clinical evaluation of autologous platelet-rich plasma therapy for intrauterine adhesions: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Study on Risk Factors Related to Intrauterine Adhesion Based on Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- The efficacy of early office hysteroscopy in preventing intrauterine adhesions after abortion: a randomized controlled trial.BMC women's health · 2024Trial
- Platelet-rich plasma as an adjuvant therapy for intrauterine adhesions: a narrative review of mechanisms, clinical efficacy and combination strategies.Annals of medicine · 2026Review
- Inflammatory cytokine signatures predict postoperative intrauterine adhesions after hysteroscopic fibroid resection: Evidence from a prospective cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
- An Injectable ROS-Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Incidence and factors associated with intrauterine adhesions: An Australian population-based longitudinal study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- A thiol-rich immunomodulatory injectable hydrogel suppresses endometrial fibrosis to restore fertilization.Science advances · 2026Article
- Hydrogel-Based Systems in Intrauterine Adhesions: Bridging the Gap from Bench to Bedside.Advanced healthcare materials · 2026Review
- Harnessing Artificial Intelligence for Regeneration of Endometrium in Asherman's Syndrome.Tissue engineering and regenerative medicine · 2026Review
- Amniotic sheets: Imaging features, subtypes, and obstetric outcomes.Abdominal radiology (New York) · 2026Review
- Platelet-derived vesicles restore fertility in endometrial injury by modulating the endometrial immune niche in mice.Science advances · 2026Article
- Asherman Syndrome in Mexican Women: Clinical Characteristics, Management, and Outcomes at a Tertiary Hospital.Journal of clinical medicine · 2026Article
- Perioperative inflammatory response as a determinant of post-myomectomy intrauterine adhesion formation.BMC women's health · 2026Observational
- HFTMSCs alleviate uterine fibrosis and restore fertility in intrauterine adhesion models.Reproductive biology and endocrinology : RB&E · 2026Article
- Unraveling the fibrotic microenvironment in intrauterine adhesions through integrated metabolomics and proteomics.BMC women's health · 2026Article
- Co-delivery of endometrial mesenchymal stem cells and macrophages by an electrospun patch promotes angiogenesis during endometrial injury repair via VEGF related signalling.Stem cell research & therapy · 2026Article
- Mechanism of Curcumin in the Treatment of Intrauterine Adhesions Based on Network Pharmacology, Molecular docking, and Experimental Validation.Biochemical genetics · 2026Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intrauterine adhesion (IUA), and its severe form Asherman syndrome (Asherman's syndrome), is a mysterious disease, often accompanied with severe clinical problems contributing to a significant impairment of reproductive function, such as menstrual disturbance (amenorrhea), infertility or recurrent pregnancy loss. Among these, its correlated infertility may be one of the most challenging problems. Although there are many etiologies for the development of IUA, uterine instrumentation is the main cause of IUA. Additionally, more complicated intrauterine surgeries can be performed by advanced technology, further increasing the risk of IUA. Strategies attempting to minimize the risk and reducing its severity are urgently needed. The current review will expand the level of our knowledge required to face the troublesome disease of IUA. It is separated into six sections, addressing the introduction of the normal cyclic endometrial repairing process and its abruption causing the formation of IUA; the etiology and prevalence of IUA; the diagnosis of IUA; the classification of IUA; the pathophysiology of IUA; and the primary prevention of IUA, including (1) delicate surgical techniques, such as the use of surgical instruments, energy systems, and pre-hysteroscopic management, (2) barrier methods, such as gels, intrauterine devices, intrauterine balloons, as well as membrane structures containing hyaluronate-carboxymethylcellulose or polyethylene oxide-sodium carboxymethylcellulose as anti-adhesive barrier.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.