Evidence map›Paper›PMID 34068164›Full record

ArticleMolecules (Basel, Switzerland)2021

Astragaloside IV Suppresses Hepatic Proliferation in Regenerating Rat Liver after 70% Partial Hepatectomy via Down-Regulation of Cell Cycle Pathway and DNA Replication.

Gyeong-Seok Lee, Hee-Yeon Jeong, Hyeon-Gung Yang, Young-Ran Seo, Eui-Gil Jung, Yong-Seok Lee, Kung-Woo Nam, Wan-Jong Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Protective Effect ofMolecules (Basel, Switzerland) · 2023
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gyeong-Seok LeeDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.
Hee-Yeon JeongDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.
Hyeon-Gung YangSoonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan 31151, Chungcheongnam-do, Korea.
Young-Ran SeoDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.
Eui-Gil JungSeoul Center, Korea Basic Science Institute, Seoul 02855, Korea.
Yong-Seok LeeDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.ORCID 0000-0001-5604-4860
Kung-Woo NamDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.
Wan-Jong KimDepartment of Life Science and Biotechnology, College of Natural Sciences, Soonchunhyang University, Asan 31538, Chungcheongnam-do, Korea.ORCID 0000-0002-2420-1291
Soonchunhyang University · KRKorea Basic Science Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astragaloside IV (AS-IV) is one of the major bio-active ingredients of huang qi which is the dried root of

Indexed as

Cell CycleDNA ReplicationDown-RegulationHepatectomyAnimalsCell ProliferationCyclin D1Gene Expression RegulationGene Regulatory NetworksHepatocyte Growth FactorLiverLiver RegenerationMaleMolecular Sequence AnnotationRatsRats, Sprague-Dawleyastragaloside ACyclin D1Hepatocyte Growth FactorRNA, MessengerSaponinsTransforming Growth Factor beta1Triterpenes70% partial hepatectomyAstragali Radixastragaloside IVAstragalus membranaceushuang qiliverliver regenerationproliferationrat

Identifiers

PMID34068164
PMCPMC8152973
OpenAlexW3162927714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.